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Abstract：
Vertebral bone quality had a significant impact on postoperative outcomes in spinal fusion surgery. New magnetic resonance imaging-based measures, such as the Vertebral Bone Quality (VBQ) score, may allow for bone quality assessment without the radiation associated with conventional testing. In the present study, we sought to assess the intrarater and interrater reliability of VBQ scores calculated by medical professionals and trainees.
Thirteen reviewers of various specialties and levels of training were recruited and asked to calculate VBQ scores for 30 patients at 2 time points separated by 2 months. Scored volumes were acquired from patients treated for both degenerative and oncologic indications. Intrarater and interrater agreement, quantified by intraclass correlation coefficient (ICC), was assessed using 2-way random effects modeling. Square-weight Cohen κ and Kendall Tau-b were used to determine whether raters assigned similar scores during both evaluations.
All raters showed moderate to excellent reliability for VBQ score (ICC 0.667-0.957; κ0.648-0.921) and excellent reliability for all constituent components used to calculate VBQ score (ICC all ≥0.97). Interrater reliability was also found to be good for VBQ score on both the first (ICC = 0.818) and second (ICC = 0.800) rounds of assessment; scores for the constituent component all had ICC values ≥0.97 for the constituent components.
The VBQ score appears to have both good intrarater and interrater reliability. In addition, there appeared to be no correlation between score reliability and level of training. External validation and further investigations of its ability to accurately model bone biomechanical properties are necessary.
Thirteen reviewers of various specialties and levels of training were recruited and asked to calculate VBQ scores for 30 patients at 2 time points separated by 2 months. Scored volumes were acquired from patients treated for both degenerative and oncologic indications. Intrarater and interrater agreement, quantified by intraclass correlation coefficient (ICC), was assessed using 2-way random effects modeling. Square-weight Cohen κ and Kendall Tau-b were used to determine whether raters assigned similar scores during both evaluations.
All raters showed moderate to excellent reliability for VBQ score (ICC 0.667-0.957; κ0.648-0.921) and excellent reliability for all constituent components used to calculate VBQ score (ICC all ≥0.97). Interrater reliability was also found to be good for VBQ score on both the first (ICC = 0.818) and second (ICC = 0.800) rounds of assessment; scores for the constituent component all had ICC values ≥0.97 for the constituent components.
The VBQ score appears to have both good intrarater and interrater reliability. In addition, there appeared to be no correlation between score reliability and level of training. External validation and further investigations of its ability to accurately model bone biomechanical properties are necessary.
摘要：
椎体骨质量对脊柱融合术后疗效有显著影响。基于磁共振成像的新措施，例如椎骨骨质量(VBQ)评分，可以在没有与常规测试相关的辐射的情况下进行骨骼质量评估。在本研究中,我们试图评估由医学专业人员和受训人员计算的VBQ分数的内部和中间可靠性.
招募了13名不同专业和培训水平的审稿人，并要求他们计算30名患者在相隔2个月的2个时间点的VBQ评分。从接受退行性和肿瘤适应症治疗的患者获得评分的体积。内部和评估者之间的协议，通过组内相关系数(ICC)量化，采用双向随机效应模型进行评估。使用平方权重Cohenκ和KendallTau-b来确定评估者在两次评估中是否分配了相似的分数。
所有评估者对VBQ评分（ICC0.667-0.957；κ0.648-0.921）显示中等至优异的可靠性，以及用于计算VBQ评分的所有构成成分（ICC均≥0.97）的优异可靠性。在第一轮（ICC=0.818）和第二轮（ICC=0.800）评估中，还发现了VBQ得分的中间可靠性；组成成分的得分均具有组成成分的ICC值≥0.97。
VBQ评分似乎具有良好的内部和中间可靠性。此外,评分可靠性和训练水平之间似乎没有相关性.有必要进行外部验证并进一步研究其准确建模骨生物力学特性的能力。
招募了13名不同专业和培训水平的审稿人，并要求他们计算30名患者在相隔2个月的2个时间点的VBQ评分。从接受退行性和肿瘤适应症治疗的患者获得评分的体积。内部和评估者之间的协议，通过组内相关系数(ICC)量化，采用双向随机效应模型进行评估。使用平方权重Cohenκ和KendallTau-b来确定评估者在两次评估中是否分配了相似的分数。
所有评估者对VBQ评分（ICC0.667-0.957；κ0.648-0.921）显示中等至优异的可靠性，以及用于计算VBQ评分的所有构成成分（ICC均≥0.97）的优异可靠性。在第一轮（ICC=0.818）和第二轮（ICC=0.800）评估中，还发现了VBQ得分的中间可靠性；组成成分的得分均具有组成成分的ICC值≥0.97。
VBQ评分似乎具有良好的内部和中间可靠性。此外,评分可靠性和训练水平之间似乎没有相关性.有必要进行外部验证并进一步研究其准确建模骨生物力学特性的能力。
