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Abstract：
OBJECTIVE: Spina bifida (SB) is a congenital birth defect defined as a failure of the neural tube formation during the embryonic development phase. Fetoscopic repair of SB is a novel treatment technique that allows to close spinal defect early and prevent potential neurological and psychomotor complications.
METHODS: We present a case report of a 32-year-old-multigravida whose fetus was diagnosed with lumbosacral myelomeningocele at 23rd week. Fetoscopic closure of MMC was performed at 26 weeks. At 32 weeks, due to premature amniorrhexis and placental abruption, an emergency C-section was performed. Newborn\'s psychomotor development was within normal limits.
CONCLUSIONS: Although intrauterine treatment has an increased risk of premature labor, placental abruption, prenatal closure is associated with improved postnatal psychomotor development. Prenatal surgery decreases the risk of Arnold-Chiari II malformation development and walking disability. Fetoscopic closure of SB is becoming a choice for treatment with beneficial outcomes for mother and fetus.
METHODS: We present a case report of a 32-year-old-multigravida whose fetus was diagnosed with lumbosacral myelomeningocele at 23rd week. Fetoscopic closure of MMC was performed at 26 weeks. At 32 weeks, due to premature amniorrhexis and placental abruption, an emergency C-section was performed. Newborn\'s psychomotor development was within normal limits.
CONCLUSIONS: Although intrauterine treatment has an increased risk of premature labor, placental abruption, prenatal closure is associated with improved postnatal psychomotor development. Prenatal surgery decreases the risk of Arnold-Chiari II malformation development and walking disability. Fetoscopic closure of SB is becoming a choice for treatment with beneficial outcomes for mother and fetus.
摘要：
目的：脊柱裂（SB）是一种先天性出生缺陷，定义为在胚胎发育阶段神经管形成失败。SB的胎儿镜修复是一种新颖的治疗技术，可以早期闭合脊柱缺损并防止潜在的神经和精神运动并发症。
方法：我们介绍一例32岁的多胎患者，其胎儿在第23周时被诊断为腰骶骨脊髓膜膨出。在26周时进行MMC的胎儿镜闭合。32周时,由于早产羊膜破裂和胎盘早剥，进行了紧急剖腹产。新生儿的精神运动发育在正常范围内。
结论：尽管宫内治疗会增加早产的风险，胎盘早剥,产前封闭与改善产后心理运动发育有关.产前手术可降低Arnold-ChiariII畸形发展和步行残疾的风险。SB的胎儿镜封堵术正在成为对母亲和胎儿有益的治疗选择。
方法：我们介绍一例32岁的多胎患者，其胎儿在第23周时被诊断为腰骶骨脊髓膜膨出。在26周时进行MMC的胎儿镜闭合。32周时,由于早产羊膜破裂和胎盘早剥，进行了紧急剖腹产。新生儿的精神运动发育在正常范围内。
结论：尽管宫内治疗会增加早产的风险，胎盘早剥,产前封闭与改善产后心理运动发育有关.产前手术可降低Arnold-ChiariII畸形发展和步行残疾的风险。SB的胎儿镜封堵术正在成为对母亲和胎儿有益的治疗选择。
