PDF(Pubmed)
Abstract：
Giant cell reparative granuloma (GCRG) is a non-neoplastic hyperplasia of bones that mostly happens in the mandible and maxilla in any age group but has a predilection for children and young adults. GCRGs that cause bone destruction are of very low frequency. Orbital-involved cases have been rarely reported since 1981, especially in children. We now report a 1-year-old girl with a rapidly enlarging post-traumatic orbital mass. CT scan and surgical resection showed a well-defined mass occupying the upper right orbit, causing bone destruction. Microscopically there was a proliferation of histocytes and some osteoclast-like multinucleated giant cells with hemosiderin, finally confirmed to be GCRG. 22 months\' follow up showed no evidence of recurrence. This case suggests infant orbital GCRG can be locally aggressive.
摘要：
巨细胞修复性肉芽肿（GCRG）是骨骼的非肿瘤性增生，主要发生在任何年龄段的下颌骨和上颌骨，但对儿童和年轻人有好感。引起骨破坏的GCRG的频率非常低。自1981年以来，很少报道涉及轨道的病例，尤其是儿童。我们现在报告一名1岁女孩，创伤后眼眶肿块迅速扩大。CT扫描和手术切除显示一个明确的肿块占据了右上眼眶，导致骨骼破坏。显微镜下可见组织细胞和一些破骨细胞样多核巨细胞与含铁血黄素的增生,最终确认为GCRG。随访22个月，无复发迹象。这种情况表明婴儿眼眶GCRG可能是局部侵袭性的。
