从越南植物到双类黄酮 , 通过触发脂质介质类转换为分辨率来缓解炎症。
关键词: 12-HHT, 12(S)-hydroxy-5-cis-8,10-trans-heptadecatrienoic acid 5-H(p)ETE, 5-hydro(pero)xy-eicosatetraenoic acid COX, cyclooxygenase DAD, diode array detector DPPH, 2,2-diphenyl-1-picrylhydrazyl ECD, electronic circular dichroism ESI, electrospray ionization FCS, fetal calf serum HPLC, high performance liquid chromatography HR, high resolution IFN, interferon IL, interleukin Inflammation LOX, lipoxygenase LT, leukotriene LTC4S, leukotriene C4 synthase Lipid mediator Lipidomics Lipoxygenase MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide MaR, maresin Natural product PBMC, peripheral blood mononuclear cells PD, protectin PG, prostaglandin PMNL, polymorphonuclear neutrophils RP, reversed phase Resolution Rv, resolvin SPE, solid phase extraction SPM, specialized pro-resolving mediators TX, thromboxane UPLC‒MS/MS, ultra-performance liquid chromatography–tandem mass spectrometry mPGES-1, microsomal prostaglandin E2 synthase 1 sEH, soluble epoxide hydrolase
来 源:
DOI:10.1016/j.apsb.2021.04.011
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