Abstract:
MELAS syndrome (Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-like episodes) is one of the most frequent mitochondrial pathologies. Its diagnosis is based on the classic triad of symptoms its acronym stands for and the presence of ragged red fibres. There is currently no curative therapy for MELAS, and treatment focuses on managing complications that affect specific organs and functions. However, some immunonutrients can be used as a therapeutic alternative in patients with MELAS. We present a scientific literature review accompanied by the clinical case of a patient with dementia and seizures admitted to the intensive care unit.
摘要:
MELAS综合征(线粒体脑病,乳酸酸中毒和中风样发作)是最常见的线粒体病变之一。它的诊断是基于其首字母缩写词代表的经典症状三联征以及参差不齐的红色纤维的存在。目前没有针对MELAS的治疗方法,治疗的重点是控制影响特定器官和功能的并发症。然而,一些免疫营养素可作为MELAS患者的治疗选择.我们提供了科学文献综述,并附有重症监护病房收治的痴呆症和癫痫患者的临床病例。