Abstract:
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder affecting 4-5% of the global population. This disorder is associated with gut microbiota, diet, sleep, and mental health. This scoping review therefore aims to map existing research that has administrated fibre-related dietary intervention to IBS individuals and reported outcomes on at least two of the three following themes: gut microbiota, sleep, and mental health. Five digital databases were searched to identify and select papers as per the inclusion and exclusion criteria. Five articles were included in the assessment, where none reported on all three themes or the combination of gut microbiota and sleep. Two studies identified alterations in gut microbiota and mental health with fibre supplementation. The other three studies reported on mental health and sleep outcomes using subjective questionnaires. IBS-related research lacks system biology-type studies targeting gut microbiota, sleep, and mental health in patients undergoing diet intervention. Further IBS research is required to explore how human gut microbiota functions (such as short-chain fatty acids) in sleep and mental health, following the implementation of dietary pattern alteration or component supplementation. Additionally, the application of objective sleep assessments is required in order to detect sleep change with more accuracy and less bias.
摘要:
肠易激综合征(IBS)是一种常见的功能性胃肠病,影响全球4-5%的人口。这种疾病与肠道微生物群有关,饮食,睡眠,和心理健康。因此,本范围审查旨在绘制已对IBS个体进行纤维相关饮食干预的现有研究,并报告了以下三个主题中至少两个的结果:肠道微生物群,睡眠,和心理健康。搜索了五个数字数据库,以根据纳入和排除标准识别和选择论文。五篇文章纳入评估,没有报道所有三个主题或肠道微生物群和睡眠的组合。两项研究确定了补充纤维会改变肠道微生物群和心理健康。其他三项研究使用主观问卷报告了心理健康和睡眠结果。IBS相关研究缺乏针对肠道微生物群的系统生物学类型研究,睡眠,以及接受饮食干预的患者的心理健康。需要进一步的IBS研究来探索人类肠道微生物群(如短链脂肪酸)在睡眠和心理健康中的作用。在实施膳食模式改变或成分补充后。此外,为了更准确、更少偏差地检测睡眠变化,需要应用客观的睡眠评估.