METHODS: A review of the recent literature on nerve regeneration was conducted in order develop further insights into the etiology of both adult onset and pediatric FS.
RESULTS: Neurturin, a neurotrophic factor released by both salivary and sweat glands, was identified as a possible key player in the etiology of FS.
CONCLUSIONS: Further research into the role of neurturin could help to elucidate the pathogenic mechanisms underlying the condition and might reveal neurturin to be a potential target for pharmacological intervention.
METHODS: NA (Basic Science Review).
方法:对最近有关神经再生的文献进行了综述,以进一步了解成人发病和儿童FS的病因。
结果:Neurturin,一种由唾液腺和汗腺释放的神经营养因子,被确定为FS病因中可能的关键参与者。
结论:对neurturin作用的进一步研究可能有助于阐明该病的致病机制,并可能揭示neurturin是药物干预的潜在靶点。
方法:NA(基础科学评论)。