关键词: Cryptosporidiosis molecular detection outbreaks waterborne transmission watery diarrhea

来  源:   DOI:10.4103/tp.TP_68_20   PDF(Pubmed)

Abstract:
Cryptosporidium spp. is one of the prime agents of infectious diarrhea. Cryptosporidium spp. has been gaining awareness as a pathogen of public health importance in India and other developing countries. Owing to the nature of multiple transmission routes such as person-to-person, animal-to-person, waterborne and foodborne, the epidemiology of cryptosporidiosis in humans is not well known. A deeper understanding of the pathogenesis may lead to better diagnosis and better treatment of the condition. Asymptomatic human and animal transmission illustrates that the spread of infection through the environment is a more plausible explanation, waterborne transmission in particular. The disease burden is underestimated and its global impact is yet to be quantified due to the lack of country-specific estimates. Assessment of the disease itself has been crucial since the morphological indistinguishability, differences in distribution and transmission, and variations in the genotypes.
摘要:
隐孢子虫。是感染性腹泻的主要病原体之一。隐孢子虫。在印度和其他发展中国家,人们一直意识到它是公共卫生重要性的病原体。由于人对人等多种传播途径的性质,动物对人,水性和食源性,人类隐孢子虫病的流行病学尚不为人所知。对发病机制的更深入了解可能会导致更好的诊断和更好的治疗。无症状的人和动物传播表明,感染通过环境传播是一个更合理的解释,特别是水性传播。由于缺乏针对具体国家的估计,疾病负担被低估,其全球影响尚待量化。由于形态学上的不可区分性,对疾病本身的评估至关重要。分布和传输的差异,和基因型的变异。
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