针对内源性大麻素系统治疗 HIV 相关神经性疼痛 : 系统评价。
关键词: 2-AG, 2-arachidonoylglycerol ABHD12, α-β-hydrolase domain-containing 12 ABHD6, α-β-hydrolase domain-containing 6 AEA, N-arachidonoylethanolamine AEs, adverse effects Antiretroviral BCP, β-caryophyllene CB1R, cannabinoid type 1 receptor CB2R, cannabinoid type 2 receptor CBD, cannabidiol CBDV, cannabidivarin CBRs, cannabinoid receptors CINP, chemotherapy-induced neuropathic pain CNS, central nervous system COX, cyclooxygenase Cannabinoid Cannabis DAG, diacylglycerol DAGL, DAG lipase DDS, descriptor differential scale DSP, distal symmetric polyneuropathy ECS, endocannabinoid system Endocannabinoid FAAH, fatty acid amide hydrolase FDA, Food and Drug Administration GPCRs, G protein-coupled receptors HIV, human immunodeficiency virus HIV-DSP, HIV-distal symmetric polyneuropathy HIV-NP, HIV-associated neuropathic pain Human immunodeficiency virus IPM, indomethacin plus minocycline L-29, palmitoylallylamide MAGL, monoacylglycerol lipase MAIDS, murine acquired immunodeficiency syndrome NAPE, N-acyl-phosphatidylethanolamine NAPE-PLD, NAPE-specific phospholipase D NP, neuropathic pain NSAIDs, non-steroidal anti-inflammatory drugs Neuropathic pain OTC, over the counter PLWH, people living with HIV PNP, peripheral neuropathic pain RCTs, randomised clinical trials SAMRC, South African Medical Research Council TRPA, transient receptor potential ankyrin TRPV, transient receptor potential vanilloid WHO, World Health Organization ddC, 2′-3′-dideoxycytidine delta-9-THC, delta-9-tetrahydrocannabinol gp, glycoprotein
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DOI:10.1016/j.ibneur.2021.01.004
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