Abstract:
In this work we used the InterDosi code to estimate photon specific absorbed fractions (SAFs) for some organs of the Zubal adult male voxelized phantom. Chemical compositions and densities of ICRP 110 adult male organs were attributed to those of the studied voxelized phantom. The SAFs of monoenergetic photons with energies ranging from 0.01 to 2 MeV, were calculated for three target regions, namely kidneys, liver, and spleen, which were the radiation source regions too. The obtained SAFs were compared to recent results obtained with the GATE code. In the GATE study, chemical compositions and densities of different organs were obtained from the ICRU report number 44. The inter-comparisons between the two studies show reasonably similar results, as 80% of the calculated SAFs are consistent within 2.5% discrepancy. This demonstrates the usefulness and applicability of the InterDosi code for internal dose calculations in a voxel-based phantom. We completed this work by studying the alpha SAFs in some organs for energies emitted by 213Bi used in targeted alpha-therapy and an analytical formula was derived for rapid alpha self-irradiation calculation in soft tissues.
摘要:
在这项工作中,我们使用InterDosi代码来估计Zubal成年男性体素化体模某些器官的光子特异性吸收分数(SAF)。ICRP110成年男性器官的化学成分和密度归因于所研究的体素化体模。能量范围为0.01至2MeV的单能光子的SAF,计算了三个目标区域,即肾脏,肝脏,和脾脏,也是辐射源区域。将获得的SAF与使用GATE代码获得的最新结果进行比较。在GATE研究中,从ICRU第44号报告中获得了不同器官的化学成分和密度。两项研究之间的相互比较显示出相当相似的结果,因为80%的计算SAF在2.5%的差异内是一致的。这证明了InterDosi代码在基于体素的体模中用于内部剂量计算的有用性和适用性。我们通过研究某些器官中的αSAF来完成这项工作,以获得靶向α治疗中使用的213Bi发出的能量,并得出了用于软组织中快速α自辐照计算的解析公式。