Abstract:
Mango is a major tropical fruit in the world and is known as the king of fruits because of its flavor, aroma, taste, and nutritional values. Although various regulatory roles of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) have been investigated in many plants, there is yet an absence of such study in mango. This is the first study to provide information on non-coding RNAs (ncRNAs) of mango with the aims of identifying miRNAs and lncRNAs and discovering their potential functions by interaction prediction of the miRNAs, lncRNAs, and their target genes. In this analysis, about a hundred miRNAs and over 7,000 temperature-responsive lncRNAs were identified and the target genes of these ncRNAs were characterized. According to these results, the newly identified mango ncRNAs, like other plant ncRNAs, have a potential role in biological and metabolic pathways including plant growth and developmental process, pathogen defense mechanism, and stress-responsive process. Moreover, mango lncRNAs can target miRNAs to reduce the stability of lncRNAs and can function as molecular decoys or sponges of miRNAs. This paper would provide information about miRNAs and lncRNAs of mango and would help for further investigation of the specific functions of mango ncRNAs through wet lab experiments.
摘要:
芒果是世界上主要的热带水果,因其风味而被称为水果之王,香气,味道,和营养价值。尽管已经在许多植物中研究了microRNAs(miRNAs)和长链非编码RNAs(lncRNAs)的各种调节作用,在芒果中还没有这样的研究。这是第一个提供芒果非编码RNA(ncRNAs)信息的研究,目的是鉴定miRNAs和lncRNAs,并通过miRNAs的相互作用预测发现它们的潜在功能。lncRNAs,和他们的目标基因。在这个分析中,鉴定了大约一百个miRNAs和超过7,000个温度响应性lncRNAs,并表征了这些ncRNAs的靶基因。根据这些结果,新鉴定的芒果ncRNAs,像其他植物ncRNAs一样,在包括植物生长和发育过程在内的生物和代谢途径中具有潜在作用,病原体防御机制,和应激反应过程。此外,芒果lncRNAs可以靶向miRNAs以降低lncRNAs的稳定性,并且可以充当miRNAs的分子诱饵或海绵。本文将提供有关芒果的miRNAs和lncRNAs的信息,并将有助于通过湿法实验室实验进一步研究芒果ncRNAs的特定功能。