关键词: Hilus cell tumour Ovarian tumour Serous cystadenomas Sex cord-stromal tumours Steroid cell tumour

来  源:   DOI:10.1186/s13048-021-00833-w   PDF(Pubmed)

Abstract:
BACKGROUND: Hilus cell tumours is considered an uncommon branch of androgen producing neoplasms that accounts for < 5% of all ovarian tumours. They are mostly benign and have characteristic gross and microscopic features. Here we present the first case of a hilus cell tumour in association with bilateral serous cystadenomas.
METHODS: A 65-year-old lady with no symptoms of virilization, presented with postmenopausal dysfunctional uterine bleeding and radiological investigations revealing bilateral ovarian cysts that required a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Gross and microscopic evaluation confirmed the diagnosis of hilus cell tumour associated with bilateral serous cystadenomas.
CONCLUSIONS: This was the first case of hilus cell tumour in association with bilateral serous cystadenomas of the ovaries. Although, majority of hilus cell tumours that have been reported in the literature were benign, further studies are required to determine the behavior of the disease.
摘要:
背景:Hilus细胞肿瘤被认为是产生雄激素的肿瘤的不常见分支,占所有卵巢肿瘤的<5%。它们大多是良性的,具有特征性的总体和微观特征。在这里,我们介绍了第一例与双侧浆液性囊腺瘤相关的门细胞肿瘤。
方法:一位没有男性化症状的65岁女士,出现绝经后功能失调性子宫出血,放射学检查显示双侧卵巢囊肿,需要经腹全子宫切除术和双侧附件卵巢切除术。大体和显微镜评估证实了与双侧浆液性囊腺瘤相关的门细胞瘤的诊断。
结论:这是第一例与双侧卵巢浆液性囊腺瘤相关的门细胞瘤。虽然,文献中报道的大多数hilus细胞肿瘤是良性的,需要进一步的研究来确定疾病的行为。
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