关键词: Etest MALDI-TOF MS Neisseria animaloris Neisseria zoodegmatis Pasteurella multocida animal bites antibiotic susceptibility

来  源:   DOI:10.1099/acmi.0.000196   PDF(Pubmed)

Abstract:
The isolation of Neisseria zoodegmatis from a 63-year-old female presenting to the emergency department following a cat bite injury to her right hand is described in this report. N. zoodegmatis , also known as Centers for Disease Control (CDC) group EF-4b, is considered to be a zoonotic pathogen, and is usually associated with dog or cat bites. Despite the potential of this organism to cause serious soft tissue infections, it can be overlooked in routine clinical laboratories due to its slow growth characteristics and when the history of animal bite is not provided to the laboratory. This case highlights the importance of appropriate clinical history provision to the microbiology laboratory to help provide important information about potential pathogens and allow microbiologists to optimize culture and identification methods. The introduction of tools such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) into clinical laboratories allows identification and the interpretation of results to be performed within a few minutes of isolation on proper culture media, as opposed to traditional methods, whose slowness may be problematic, as shown in this case report.
摘要:
本报告描述了从一只63岁的女性中分离出的动物奈瑟氏菌,该女性在右手被猫咬伤后出现在急诊科。N.zoodegmatis,也被称为疾病控制中心(CDC)组EF-4b,被认为是人畜共患病原体,通常与狗或猫咬伤有关。尽管这种生物有可能导致严重的软组织感染,由于其缓慢的生长特征以及未向实验室提供动物咬伤史,因此在常规临床实验室中可能会忽略它。此案例强调了向微生物实验室提供适当的临床病史的重要性,以帮助提供有关潜在病原体的重要信息,并允许微生物学家优化培养和鉴定方法。将基质辅助激光解吸/电离飞行时间质谱(MALDI-TOFMS)等工具引入临床实验室,可以在适当的培养基上分离后几分钟内进行鉴定和结果解释。与传统方法相反,他们的缓慢可能是有问题的,如案例报告所示。
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