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Abstract：
UNASSIGNED: Dengue shock syndrome (DSS) in children is a challenging infectious disease due to its high mortality rate. Several factors can contribute to the DSS patients\' outcomes. Here we defined factors associated with clinical outcomes of patients with DSS in Pediatric Intensive Care Unit (PICU).
UNASSIGNED: We retrospectively collected data from January 2016 to May 2020 of patients who had been diagnosed with DSS and admitted to PICU in our tertiary referral hospital. Bivariate analysis and logistic regression were used to evaluate independent predictors of the study outcomes.
UNASSIGNED: Overall, 146 patients were enrolled in this study, including 53.4% males and 46.6% females. The mortality rate during the study period was 5.5%. Fluid overload percentage, shock condition at PICU admission, DIC, and AKI were independent predictors for DSS mortality in logistic regression test with p < 0.05. There were several factors correlated with prolonged stay, including disseminated intravascular coagulation (DIC) (RR 15.26; 95% CI: 4.97-46.81), and nutritional status (RR 16.47; 95% CI: 3.72-72.9).
UNASSIGNED: Fluid overload percentage, shock condition at PICU admission, DIC, and AKI are independent predictors for DSS mortality. Several factors contribute to prolonged PICU stay, including DIC and nutritional status.
UNASSIGNED: We retrospectively collected data from January 2016 to May 2020 of patients who had been diagnosed with DSS and admitted to PICU in our tertiary referral hospital. Bivariate analysis and logistic regression were used to evaluate independent predictors of the study outcomes.
UNASSIGNED: Overall, 146 patients were enrolled in this study, including 53.4% males and 46.6% females. The mortality rate during the study period was 5.5%. Fluid overload percentage, shock condition at PICU admission, DIC, and AKI were independent predictors for DSS mortality in logistic regression test with p < 0.05. There were several factors correlated with prolonged stay, including disseminated intravascular coagulation (DIC) (RR 15.26; 95% CI: 4.97-46.81), and nutritional status (RR 16.47; 95% CI: 3.72-72.9).
UNASSIGNED: Fluid overload percentage, shock condition at PICU admission, DIC, and AKI are independent predictors for DSS mortality. Several factors contribute to prolonged PICU stay, including DIC and nutritional status.
摘要：
■儿童登革热休克综合征（DSS）是一种具有挑战性的传染病，由于其高死亡率。有几个因素可以影响DSS患者的预后。在这里，我们定义了与儿科重症监护病房（PICU）中DSS患者临床结局相关的因素。
我们回顾性收集了2016年1月至2020年5月在我们的三级转诊医院被诊断为DSS并入住PICU的患者的数据。双变量分析和逻辑回归用于评估研究结果的独立预测因子。
■总的来说，146名患者参加了这项研究，其中男性占53.4%,女性占46.6%。研究期间的死亡率为5.5%。流体过载百分比,PICU入院时的休克状况，DIC,在Logistic回归检验中，AKI是DSS死亡率的独立预测因子，p<0.05。有几个因素与长期逗留有关，包括弥散性血管内凝血（DIC）（RR15.26；95%CI：4.97-46.81），和营养状况（RR16.47；95%CI：3.72-72.9）。
■流体过载百分比，PICU入院时的休克状况，DIC,和AKI是DSS死亡率的独立预测因子。几个因素导致PICU住院时间延长，包括DIC和营养状况。
我们回顾性收集了2016年1月至2020年5月在我们的三级转诊医院被诊断为DSS并入住PICU的患者的数据。双变量分析和逻辑回归用于评估研究结果的独立预测因子。
■总的来说，146名患者参加了这项研究，其中男性占53.4%,女性占46.6%。研究期间的死亡率为5.5%。流体过载百分比,PICU入院时的休克状况，DIC,在Logistic回归检验中，AKI是DSS死亡率的独立预测因子，p<0.05。有几个因素与长期逗留有关，包括弥散性血管内凝血（DIC）（RR15.26；95%CI：4.97-46.81），和营养状况（RR16.47；95%CI：3.72-72.9）。
■流体过载百分比，PICU入院时的休克状况，DIC,和AKI是DSS死亡率的独立预测因子。几个因素导致PICU住院时间延长，包括DIC和营养状况。
