COVID - 19 和 RA 共有一个驱动 PD - L1 + 中性粒细胞和 CD14 + 单核细胞的 SPP1 髓样途径。
关键词: Autoimmune diseases Infectious disease Inflammation Macrophages
Mesh : Arthritis, Rheumatoid / immunology metabolism B7-H1 Antigen / immunology Bronchoalveolar Lavage Fluid / immunology CD48 Antigen / immunology COVID-19 / chemically induced immunology metabolism Fatty Acid-Binding Proteins / immunology Humans Lectins / immunology Lipopolysaccharide Receptors / immunology metabolism Lung / diagnostic imaging immunology metabolism pathology Macrophages / immunology metabolism Membrane Glycoproteins / immunology Monocytes / immunology metabolism Neutrophils / immunology metabolism Osteopontin / blood immunology Receptor Protein-Tyrosine Kinases / metabolism Receptors, Immunologic / immunology S100A12 Protein / immunology metabolism Synovial Membrane / immunology Tomography, X-Ray Computed Ficolins
来 源:
DOI:10.1172/jci.insight.147413
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