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Abstract：
UNASSIGNED: Conventional cancer treatments such as radical surgery and systemic therapy targeting the organ or organ system might have side effects because of damage to the surrounding tissue. For this reason, there is a need for new instruments that focally treat cancer.
UNASSIGNED: This review provides a comprehensive overview of the patent literature on minimally and noninvasive focal therapy instruments to treat localized cancer. The medical section of the Google Patents database was scanned, and 128 patents on focal therapy instruments published in the last two decades (2000-2021) were retrieved and classified. The classification is based on the treatment target (cancer cell or network of cancer cells), treatment purpose (destroy the cancerous structure or disable its function), and treatment means (energy, matter, or a combination of both).
UNASSIGNED: We found patents describing instruments for all groups, except for the instruments that destroy a cancer cell network structure by applying matter (e.g. particles) to the network. The description of the different treatment types may serve as a source of inspiration for new focal therapy instruments to treat localized cancer.
UNASSIGNED: This review provides a comprehensive overview of the patent literature on minimally and noninvasive focal therapy instruments to treat localized cancer. The medical section of the Google Patents database was scanned, and 128 patents on focal therapy instruments published in the last two decades (2000-2021) were retrieved and classified. The classification is based on the treatment target (cancer cell or network of cancer cells), treatment purpose (destroy the cancerous structure or disable its function), and treatment means (energy, matter, or a combination of both).
UNASSIGNED: We found patents describing instruments for all groups, except for the instruments that destroy a cancer cell network structure by applying matter (e.g. particles) to the network. The description of the different treatment types may serve as a source of inspiration for new focal therapy instruments to treat localized cancer.
摘要：
■常规癌症治疗如根治性手术和靶向器官或器官系统的全身治疗可能由于对周围组织的损伤而具有副作用。出于这个原因,需要新的治疗局部癌症的仪器。
■这篇综述提供了有关治疗局部癌症的微创和非侵入性局灶性治疗仪器的专利文献的全面概述。谷歌专利数据库的医疗部分被扫描，检索并分类了过去二十年（2000-2021年）中发布的128项聚焦治疗仪器专利。分类基于治疗目标（癌细胞或癌细胞网络），治疗目的（破坏癌变结构或禁用其功能），和治疗手段(能量，物质，或两者的组合)。
■我们发现了为所有群体描述仪器的专利，除了通过将物质（例如颗粒）应用于网络来破坏癌细胞网络结构的仪器。不同治疗类型的描述可以作为新的聚焦治疗仪器治疗局部癌症的灵感来源。
■这篇综述提供了有关治疗局部癌症的微创和非侵入性局灶性治疗仪器的专利文献的全面概述。谷歌专利数据库的医疗部分被扫描，检索并分类了过去二十年（2000-2021年）中发布的128项聚焦治疗仪器专利。分类基于治疗目标（癌细胞或癌细胞网络），治疗目的（破坏癌变结构或禁用其功能），和治疗手段(能量，物质，或两者的组合)。
■我们发现了为所有群体描述仪器的专利，除了通过将物质（例如颗粒）应用于网络来破坏癌细胞网络结构的仪器。不同治疗类型的描述可以作为新的聚焦治疗仪器治疗局部癌症的灵感来源。
