关键词: electrophysiology optic nerve primary congenital glaucoma visual evoked potentials

来  源:   DOI:10.2147/OPTH.S312163   PDF(Pubmed)

Abstract:
UNASSIGNED: To evaluate the VEP parameters in operated controlled primary congenital glaucoma (PCG) eyes and compare them to normal age similar children eyes.
UNASSIGNED: A cross-sectional comparative study conducted on 34 (19 right) eyes of 26 (19 males) children operated for PCG and 30 (17 right) eyes of 22 (12 males) age similar control children in a university-based practice. All study participants were subjected to a standard protocol of examination and electrophysiological testing (single flash VEP response, light adapted, pupils not dilated), reporting on the P2 implicit time, N1-P1 and N2-P2 (amplitude).
UNASSIGNED: The mean±SD of the age of the study children and controls was 43.22±33.2 and 55.68±35.2 months respectively (p=0.217). The mean±SD IOP and cup/disc ratio of the study children were 18.4±5.2 and 5.2±3.3mmHg and 0.7±0.2 and 0.3±0.3 at presentation and at testing, respectively. The VEP testing was conducted after 21.5±21.3 months of surgery for PCG. There was no statistically significant differences in P2, N1-P1 and N2-P2 between patients and controls (p=0.941, 0.916,0.945, respectively). There was no statistically significant correlation between most of the clinical characteristics of the study eyes and any of the studied VEP parameters.
UNASSIGNED: Operated controlled PCG eyes have VEP parameters that match their normal fellow children.
摘要:
评估手术控制的原发性先天性青光眼(PCG)眼的VEP参数,并将其与正常年龄相似的儿童眼进行比较。
一项横断面比较研究,对26名(19名男性)接受PCG手术的儿童的34只(19只右)眼和22名(12名男性)年龄相似的对照儿童的30只(17只右)眼进行了一项基于大学的实践。所有研究参与者都接受了标准的检查和电生理测试方案(单次闪光VEP反应,光线适应,瞳孔未扩张),报告P2隐式时间,N1-P1和N2-P2(振幅)。
研究儿童和对照组年龄的平均值±SD分别为43.22±33.2和55.68±35.2个月(p=0.217)。在演示和测试时,研究儿童的平均±SDIOP和杯/盘比率分别为18.4±5.2和5.2±3.3mmHg和0.7±0.2和0.3±0.3,分别。在PCG手术21.5±21.3个月后进行VEP测试。患者和对照组之间的P2,N1-P1和N2-P2没有统计学上的显着差异(分别为p=0.941,0.916,0.945)。研究眼睛的大多数临床特征与任何研究的VEP参数之间没有统计学上的显着相关性。
操作控制的PCG眼睛的VEP参数与其正常的同伴孩子相匹配。
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