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Abstract：
The outbreak of SARS-CoV-2 has been an extraordinary event that constituted a global health emergency. As the novel coronavirus is continuing to spread over the world, the need for therapeutic agents to control this pandemic is increasing. αV β6 Integrin may be an intriguing target not only for the inhibition of SARS-CoV-2 entry, but also for the diagnosis/treatment of COVID-19 related fibrosis, an emerging type of fibrotic disease which will probably affect a significant part of the recovered patients. In this short article, the possible role of this integrin for fighting COVID-19 is discussed on the basis of recently published evidence, showing how its underestimated involvement may be interesting for the development of novel pharmacological tools.
摘要：
SARS-CoV-2的爆发是一个非同寻常的事件，构成了全球卫生紧急情况。随着新型冠状病毒继续在世界各地传播，控制这种大流行的治疗剂的需求正在增加。αVβ6整合素可能不仅是抑制SARS-CoV-2进入的一个有趣的靶标，而且还用于COVID-19相关纤维化的诊断/治疗，一种新出现的纤维化疾病，可能会影响大部分康复患者。在这篇短文中,根据最近发表的证据，讨论了这种整合素在对抗COVID-19中的可能作用，显示其被低估的参与可能对新型药理工具的开发很有趣。
