Abstract：
Two separated incisions are generally adopted in breast cancer patients treated by mastectomy plus sentinel lymph node biopsy (SLNB). However, one-incision procedure is also applied in clinical practice. The outcomes of the two different surgical strategies remain unknown. This issue needs to be investigated. The medical records of breast cancer patients who underwent a mastectomy combined with an SLNB were reviewed retrospectively. Group A comprised patients who received a single incision for both the mastectomy and SLNB. Group B comprised patients who received a second incision for the SLNB. Demographics and outcomes were compared between the two groups. There were 280 female patients divided into Groups A (n = 130) and B (n = 150) included in this study. Preoperatively, the two groups were similar in demographics for age, tumor size, tumor location, body mass index, pathologic type, and cancer stage (P > 0.05). Group A showed shorter surgical times (129.5 ± 29.0 vs. 136.7 ± 21.9 min), less postoperative upper limb numbness (12.3% vs. 25.3%), and more harvested sentinel lymph nodes (3.2 ± 1.1 vs. 2.7 ± 1.0) than Group B (P < 0.05). There were no significant differences for intraoperative blood loss, total postoperative drainage amount, hospital stay, upper limb motility, upper limb pain, upper limb edema, number of metastatic sentinel lymph nodes, follow-up time, or recurrent cases (P > 0.05). The one-incision approach for a breast cancer mastectomy plus SLNB has several advantages over the two-incision approach, including a shorter surgical time, decreased upper limb numbness, and the harvesting of more sentinel lymph nodes. Further prospective randomized controlled clinical trials should be designed to verify the current findings.
摘要：
通过乳房切除术加前哨淋巴结活检（SLNB）治疗的乳腺癌患者通常采用两个分开的切口。然而,单切口手术也应用于临床实践。两种不同的手术策略的结果仍然未知。这个问题需要调查。回顾性分析了接受乳房切除术合并SLNB的乳腺癌患者的病历。A组包括同时接受乳房切除术和SLNB的单个切口的患者。B组包括接受SLNB第二次切口的患者。比较两组的人口统计学特征和结果。本研究包括280名女性患者，分为A组（n=130）和B组（n=150）。术前,两组的人口统计学年龄相似，肿瘤大小,肿瘤位置,身体质量指数,病理类型,和癌症分期(P>0.05)。A组显示手术时间较短（129.5±29.0vs.136.7±21.9分钟),术后上肢麻木较少（12.3%vs.25.3%），和更多的前哨淋巴结（3.2±1.1vs.2.7±1.0)比B组(P<0.05)。术中失血量无显著差异,术后引流总量,住院,上肢运动,上肢疼痛,上肢水肿,转移性前哨淋巴结的数量，随访时间,或复发病例(P>0.05)。单切口方法用于乳腺癌乳房切除术加SLNB与双切口方法相比有几个优点。包括更短的手术时间，上肢麻木减少，采集更多的前哨淋巴结.应设计进一步的前瞻性随机对照临床试验来验证当前的发现。
