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Abstract：
UNASSIGNED: We report a case series of 4 patients with type 1 diabetes who used hybrid closed-loop insulin pumps (Medtronic MiniMed 670 G) during hospitalization.
UNASSIGNED: Clinical data and point-of-care glucose values are presented for each patient. Glucose values are shown graphically while in manual mode as well as in auto mode.
UNASSIGNED: The first case was a 30-year-old man admitted for pancreatitis. Mean point-of-care blood glucose was 165.7 mg/dL while in auto mode, without hypoglycemia, compared with 221 mg/dL while in manual mode. The second case was a 28-year-old woman who was admitted for a laparoscopic cholecystectomy. Mean point-of-care blood glucose in auto mode was 131.3 mg/dL, without hypoglycemia, compared with 117.6 mg/dL while in manual mode. The third case was a 46-year-old man admitted to the intensive care unit for influenzal pneumonia. Mean point-of-care blood glucose in auto mode was 159.1 mg/dL without hypoglycemia, compared with 218.5 mg/dL while in manual mode. The fourth case was a 60-year-old man who remained in auto mode throughout his hospitalization except for a period when he removed his pump for an endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. His mean point-of-care blood glucose while in auto mode was 156.8 mg/dL without hypoglycemia.
UNASSIGNED: These case reports support the use of hybrid closed-loop insulin-pump therapy in the inpatient setting to maintain inpatient glycemic targets and avoid hypoglycemia when part of an institution-sanctioned strategy for safe use of insulin pumps that includes point-of-care blood glucose monitoring.
UNASSIGNED: Clinical data and point-of-care glucose values are presented for each patient. Glucose values are shown graphically while in manual mode as well as in auto mode.
UNASSIGNED: The first case was a 30-year-old man admitted for pancreatitis. Mean point-of-care blood glucose was 165.7 mg/dL while in auto mode, without hypoglycemia, compared with 221 mg/dL while in manual mode. The second case was a 28-year-old woman who was admitted for a laparoscopic cholecystectomy. Mean point-of-care blood glucose in auto mode was 131.3 mg/dL, without hypoglycemia, compared with 117.6 mg/dL while in manual mode. The third case was a 46-year-old man admitted to the intensive care unit for influenzal pneumonia. Mean point-of-care blood glucose in auto mode was 159.1 mg/dL without hypoglycemia, compared with 218.5 mg/dL while in manual mode. The fourth case was a 60-year-old man who remained in auto mode throughout his hospitalization except for a period when he removed his pump for an endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. His mean point-of-care blood glucose while in auto mode was 156.8 mg/dL without hypoglycemia.
UNASSIGNED: These case reports support the use of hybrid closed-loop insulin-pump therapy in the inpatient setting to maintain inpatient glycemic targets and avoid hypoglycemia when part of an institution-sanctioned strategy for safe use of insulin pumps that includes point-of-care blood glucose monitoring.
摘要：
■我们报告了4例1型糖尿病患者的病例系列，这些患者在住院期间使用了混合闭环胰岛素泵（MedtronicMiniMed670G）。
呈现每位患者的临床数据和护理点葡萄糖值。在手动模式以及自动模式下,葡萄糖值以图形方式显示。
第一个病例是一名30岁的男子因胰腺炎入院。在自动模式下，平均护理点血糖为165.7mg/dL，没有低血糖，与手动模式下的221mg/dL相比。第二例是一名28岁的妇女，她接受了腹腔镜胆囊切除术。自动模式下的平均护理点血糖为131.3mg/dL，没有低血糖，与手动模式下的117.6mg/dL相比。第三例是一名46岁的男子因流感肺炎而入住重症监护室。自动模式下的平均即时血糖为159.1mg/dL，无低血糖，与手动模式下的218.5mg/dL相比。第四例是一名60岁的男子，他在整个住院期间一直处于自动模式，除了一段时间外，他取出泵进行内窥镜逆行胰胆管造影术和内窥镜超声检查。在自动模式下，他的平均即时血糖为156.8mg/dL，无低血糖。
这些病例报告支持在住院患者中使用混合闭环胰岛素泵治疗，以维持住院患者的血糖目标并避免低血糖，这是机构认可的安全使用胰岛素泵策略的一部分，包括即时血糖监测。
呈现每位患者的临床数据和护理点葡萄糖值。在手动模式以及自动模式下,葡萄糖值以图形方式显示。
第一个病例是一名30岁的男子因胰腺炎入院。在自动模式下，平均护理点血糖为165.7mg/dL，没有低血糖，与手动模式下的221mg/dL相比。第二例是一名28岁的妇女，她接受了腹腔镜胆囊切除术。自动模式下的平均护理点血糖为131.3mg/dL，没有低血糖，与手动模式下的117.6mg/dL相比。第三例是一名46岁的男子因流感肺炎而入住重症监护室。自动模式下的平均即时血糖为159.1mg/dL，无低血糖，与手动模式下的218.5mg/dL相比。第四例是一名60岁的男子，他在整个住院期间一直处于自动模式，除了一段时间外，他取出泵进行内窥镜逆行胰胆管造影术和内窥镜超声检查。在自动模式下，他的平均即时血糖为156.8mg/dL，无低血糖。
这些病例报告支持在住院患者中使用混合闭环胰岛素泵治疗，以维持住院患者的血糖目标并避免低血糖，这是机构认可的安全使用胰岛素泵策略的一部分，包括即时血糖监测。
