Abstract:
Sarcoidosis is a systemic granulomatous disease with heterogenous clinical manifestations. Here we review the diagnosis of sarcoidosis and propose a clinically feasible diagnostic work-up and monitoring protocol. As sarcoidosis is a systemic disease, a multidisciplinary approach is recommended for best outcomes. However, since the lungs are frequently involved, the pulmonologist is often the referral physician for diagnosis and management. When sarcoidosis is suspected, diagnosis needs to be confirmed and organ involvement/impairment assessed. This process is also required to establish whether the patient is likely to benefit from treatment, as many cases of sarcoidosis are self-limited and remit spontaneously. Whether or not treatment is started, effective regular follow-up is necessary to monitor changes in the disease, including extension, progression, remissions, flare-ups, and complications.
摘要:
结节病是一种全身性肉芽肿性疾病,临床表现不均匀。在这里,我们回顾了结节病的诊断,并提出了临床上可行的诊断检查和监测方案。由于结节病是一种全身性疾病,建议采用多学科方法获得最佳结果.然而,因为肺部经常受累,肺科医师通常是诊断和治疗的转诊医师。当怀疑结节病时,需要确诊并评估器官受累/损伤.这个过程也需要确定患者是否可能从治疗中受益,由于许多结节病病例是自我限制的,并且是自发缓解的。无论是否开始治疗,有效的定期随访对于监测疾病的变化是必要的,包括扩展,programming,remissions,爆发,和并发症。