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Abstract：
The aim of this study was to determine the effect of lipodystrophy on self-esteem and adherence to antiretroviral therapy (ART) in people living with HIV (PLHIV). A cross-sectional and comparative study was carried out in an infection clinic, with 125 patients with lipodystrophy and 125 without lipodystrophy. Sociodemographic, clinical and epidemiological data were collected, using the Rosenberg Self-Esteem Scale and Assessment of Adherence to Antiretroviral Treatment Questionnaire (CEAT-VIH). Descriptive statistics and univariate and multivariate logistic regression analysis were used. Of the total sample, 57.2% had unsatisfactory self-esteem and 57.6% adequate adherence to ART. Self-esteem was lower in PLHIV with lipodystrophy (66.4%). PLHIV with monthly income less than or equal to two minimum wages (P < 0.001) and those with lipodystrophy had more unsatisfactory self-esteem (P < 0.001). Catholics had better self-esteem (P = 0.012), when compared to those without religion. Patients with monthly income less than or equal to two minimum wages (P = 0.021) and people with unsatisfactory self-esteem had more inadequate adherence to ART (P = 0.001). Catholics had better adherence to antiretrovirals (P = 0.007). In conclusion, lipodystrophy and low income negatively affect the self-esteem of PLHIV. Low income and unsatisfactory self-esteem make adherence to ART difficult. Religion is a protective factor for satisfactory self-esteem and adherence to antiretrovirals.
摘要：
这项研究的目的是确定脂肪营养不良对HIV（PLHIV）感染者的自尊和坚持抗逆转录病毒治疗（ART）的影响。在感染诊所进行了横断面和比较研究，125例脂肪营养不良患者和125例无脂肪营养不良患者。社会人口统计学，收集临床和流行病学数据，使用Rosenberg自尊量表和抗逆转录病毒治疗依从性评估问卷（CEAT-VIH）。使用描述性统计以及单变量和多变量逻辑回归分析。在总样本中，57.2％的自尊心不满意，57.6％的人对ART的依从性不足。患有脂肪营养不良的PLHIV患者的自尊较低(66.4%)。月收入小于或等于两个最低工资（P<0.001）的PLHIV和患有脂肪营养不良的人的自尊心更加不令人满意（P<0.001）。天主教徒有更好的自尊（P=0.012），与没有宗教的人相比。月收入小于或等于两个最低工资（P=0.021）的患者和自尊不满意的人对ART的依从性更高（P=0.001）。天主教徒对抗逆转录病毒药物的依从性更好（P=0.007）。总之,脂肪营养不良和低收入对PLHIV的自尊产生负面影响。低收入和不满意的自尊使坚持ART变得困难。宗教是令人满意的自尊和坚持抗逆转录病毒药物的保护因素。
