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Abstract：
Phthalates are a series of widely used chemicals that demonstrate to be endocrine disruptors and are detrimental to human health. Phthalates can be found in most products that have contact with plastics during producing, packaging, or delivering. Despite the short half-lives in tissues, chronic exposure to phthalates will adversely influence the endocrine system and functioning of multiple organs, which has negative long-term impacts on the success of pregnancy, child growth and development, and reproductive systems in both young children and adolescents. Several countries have established restrictions and regulations on some types of phthalates; however, we think that more countries should establish constraints or substitute measures for phthalates to reduce health risks. This article aims to summarize the adverse impacts of phthalates on human health, analyze the toxicity mechanism, assess the risks, and finally provide feasible strategies to reduce exposure of the public to phthalates.
摘要：
邻苯二甲酸盐是一系列广泛使用的化学物质，被证明是内分泌干扰物，对人体健康有害。邻苯二甲酸盐可以在生产过程中与塑料接触的大多数产品中找到，包装,或交付。尽管组织的半衰期很短，长期接触邻苯二甲酸酯会对内分泌系统和多个器官的功能产生不利影响，这对怀孕的成功有负面的长期影响，儿童成长和发展，儿童和青少年的生殖系统。一些国家已经对某些类型的邻苯二甲酸酯建立了限制和法规；然而，我们认为，更多的国家应该建立限制或替代邻苯二甲酸盐的措施，以降低健康风险。本文旨在总结邻苯二甲酸酯对人类健康的不利影响,分析毒性机制，评估风险，最后提供可行的策略，以减少公众对邻苯二甲酸酯的暴露。
