关键词: Angiosarcoma Primary cardiac angiosarcoma (PCAS). chest computed tomography heart nodules

来  源:   DOI:10.2174/1573405617666210521151753

Abstract:
Primary cardiac angiosarcoma is a rare malignancy with high predilection to involve surrounding structures such as pulmonary metastases. We analysed the chest computed tomography (CT) imaging features of patients diagnosed with primary cardiac angiosarcoma with pulmonary metastases in this study.
This study retrospectively reviewed 12 patients with confirmed primary cardiac angiosarcoma, out of which eight (all men) with pulmonary metastasis were included in the analysis. The patients\' age ranged from 17 to 74 (mean: 48) years. CT was performed in all patients with unenhanced, contrast-enhanced, and both scans were done in 1, 3 and 4 patients, respectively.
Nodular lesions were observed in 7 patients with multiple solid nodules observed in 6 out of 7 patients. A solitary solid nodule was found in the remaining patient in the upper lobe and apical segment of the right lung with a diameter of 11.7 mm. All solid nodules were distributed along with bronchovascular bundles in the lungs, and their maximum diameter ranged from 2.3 to 19.9 mm. Nodules larger than 10 mm in diameter were heterogeneously enhanced on contrast-enhanced CT images (5/8 patients), whereas those smaller than 10 mm were homogeneously enhanced (3/8 patients). Other imaging features, namely the tree-in-bud pattern, emphysema, pleural effusion, and mediastinal lymph node enlargement, were observed in 4, 3, 3, and 2 patients, respectively.
CT enhancement features of pulmonary metastasis in patients with primary cardiac angiosarcoma depend on the size of pulmonary nodules, with larger ones being heterogeneous and smaller ones homogeneous. Other signs are less noticed.
摘要:
原发性心脏血管肉瘤是一种罕见的恶性肿瘤,易累及周围结构,例如肺转移。在这项研究中,我们分析了诊断为原发性心脏血管肉瘤伴肺转移的患者的胸部计算机断层扫描(CT)影像学特征。
本研究回顾性分析了12例确诊为原发性心脏血管肉瘤的患者,其中8例(均为男性)肺转移纳入分析。患者年龄17~74岁(平均48岁)。所有未增强的患者均进行了CT检查,对比度增强,对1、3和4名患者进行了两次扫描,分别。
在7例患者中观察到结节病变,在7例患者中有6例观察到多个实性结节。其余患者在右肺的上叶和心尖段发现了一个孤立的实性结节,直径为11.7mm。所有实性结节与支气管血管束一起分布在肺中,它们的最大直径范围为2.3至19.9毫米。直径大于10mm的结节在对比增强CT图像上不均匀增强(5/8例),而小于10mm的患者则均匀增强(3/8例)。其他成像功能,即树芽模式,肺气肿,胸腔积液,纵隔淋巴结肿大,在4、3、3和2名患者中观察到,分别。
原发性心脏血管肉瘤患者肺转移的CT增强特征取决于肺结节的大小,较大的是异质的,较小的是同质的。其他迹象很少被注意到。
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