PDF(Pubmed)
Abstract：
Independent Cushing\'s adrenocorticotropic hormone (ACTH) syndrome can have several causes, including adrenal carcinoma or simple adrenal hyperplasia. Although the distinction between malignant and benign can be effectively made through imaging investigations, in the situation where there are bilateral formations, their hormonal activity is impossible to appreciate via non-invasive techniques. The present study includes the presentation of a clinical case on the basis of which a literature review was made. The clinical case pertains to a 32-year-old patient with ACTH-independent Cushing\'s syndrome and bilateral adrenal tumor formations leading to the utility of adrenal venous sampling to avoid bilateral adrenalectomy. A literature review was subsequently conducted focusing on articles pertaining to the PICO criteria in order to describe: The diagnosis of adrenal tumor masses, the decision on the type of surgery and most importantly, the impact of adrenal venous sampling in avoiding surgical resection. These interventions severely limit the patients\' quality of life.
摘要：
独立库欣的促肾上腺皮质激素（ACTH）综合征可以有几个原因，包括肾上腺癌或单纯性肾上腺增生。尽管通过影像学检查可以有效区分恶性和良性，在有双边编队的情况下，它们的荷尔蒙活动是不可能通过非侵入性技术来欣赏的。本研究包括一个临床病例的介绍，在此基础上进行了文献综述。该临床病例涉及一名32岁的ACTH非依赖性库欣综合征和双侧肾上腺肿瘤形成患者，导致使用肾上腺静脉采样以避免双侧肾上腺切除术。随后进行了文献综述，重点关注与PICO标准有关的文章，以描述：肾上腺肿瘤肿块的诊断，决定手术类型，最重要的是，肾上腺静脉采样对避免手术切除的影响。这些干预措施严重限制了患者的生活质量。
