PDF(Pubmed)
Abstract：
Syringomas are benign tumors originating from the intraepidermal portion of eccrine sweat ducts. A six-year-old African American female presented with multiple 2-3 mm hyperpigmented papules over the neck, upper chest, and axillae bilaterally. The lesions were non-tender, non-pruritic, and did not bleed when lightly scraped. A café-au-lait macule was incidentally found in the mid-back of the patient. Histopathologically, multiple small ducts displaying a tadpole-shaped/paisley-tie pattern with fibrotic stroma were identified on hematoxylin and eosin staining. Epithelium showing nests of cells with basaloid appearance and dilated glands filled with eosinophilic material were also identified. These histopathologic findings were consistent with a diagnosis of eruptive syringoma. The patient was treated conservatively, and the lesions subsided without intervention. In most patients requesting treatment, isotretinoin is used; however, this may be an unnecessary measure in many patients. Overall, this case was significant due to the patient\'s young age, ethnicity, and clinical improvement in the absence of treatment.
摘要：
汗管瘤是起源于内分泌汗腺导管的表皮内部分的良性肿瘤。一名6岁的非洲裔美国女性颈部出现多个2-3毫米色素沉着丘疹，上胸部,和两侧的腋窝。病变没有触痛,非瘙痒,轻轻刮擦时没有流血。偶然在患者的中背发现了一个咖啡斑。组织病理学,在苏木精和曙红染色中发现了多个小导管，这些导管显示出a形/佩斯利领带图案并伴有纤维化基质。还鉴定了上皮，其显示出具有基底细胞样外观的细胞巢和充满嗜酸性物质的腺体。这些组织病理学发现与发疹性汗管瘤的诊断一致。病人接受了保守治疗,病变在没有干预的情况下消退。在大多数要求治疗的患者中，使用异维A酸；然而，这对许多患者来说可能是不必要的措施。总的来说,由于患者的年龄较小，该病例意义重大，种族,以及在没有治疗的情况下的临床改善。
