早期发病患者的外显子组测序支持结直肠癌的遗传异质性。
Mesh : Adult Colorectal Neoplasms / genetics pathology DNA Helicases / genetics DNA Repair Enzymes / genetics DNA-Binding Proteins / genetics Exome Female Gene Expression Regulation, Neoplastic Genetic Heterogeneity Genetic Predisposition to Disease Humans Male Methyltransferases / genetics Middle Aged Poly-ADP-Ribose Binding Proteins / genetics Protein Tyrosine Phosphatase, Non-Receptor Type 13 / genetics Whole Exome Sequencing
来 源:
DOI:10.1038/s41598-021-90590-z
PDF(Sci-hub)
PDF(Pubmed)