Abstract：
Skin and soft tissue infections (SSTIs) are a large group of diseases with a wide range of clinically different conditions, some of which can be immediately life-threatening. A number of bacteria play an important role in the etiology of SSTIs, especially gram-positive cocci Staphylococcus aureus and Streptococcus pyogenes. In this case report, a young woman with skin defects after a fasciotomy was treated using a dermal substitute application. Multiple infectious complications in the skin and soft tissues with a high risk of development of phlebitis and with significant intolerance to a variety of antimicrobials were observed. The dramatic SSTI was treated using intravenous administration of dalbavancin, a very potent bactericidal antibiotic representing a rational option in the treatment of SSTIs caused by gram-positive bacteria.
摘要：
皮肤和软组织感染（STTI）是一大类疾病，具有广泛的临床不同条件，其中一些可能会立即危及生命。许多细菌在SSTIs的病因中起着重要作用，尤其是革兰氏阳性球菌金黄色葡萄球菌和化脓性链球菌。在这个案例报告中,一名在筋膜切开术后有皮肤缺陷的年轻女性接受了真皮替代品的治疗。观察到皮肤和软组织中的多种感染并发症，发生静脉炎的风险很高，并且对各种抗菌药物有明显的不耐受。戏剧性的SSTI使用dalbavancin的静脉给药进行治疗，一种非常有效的杀菌抗生素，代表了治疗革兰氏阳性菌引起的SSTI的合理选择。
