关键词: Pulmonary hypertension autism spectrum disorder iron deficiency right-sided heart failure vitamin C deficiency

Mesh : Male Child Humans Scurvy / complications diagnosis drug therapy Autism Spectrum Disorder / complications diagnosis Hypertension, Pulmonary / diagnosis drug therapy etiology Heart Failure / etiology complications Ascorbic Acid / therapeutic use

来  源:   DOI:10.1080/20469047.2021.1901406   PDF(Sci-hub)

Abstract:
Scurvy, a condition caused by vitamin C deficiency, is rare, especially in high-income countries. Symptoms of scurvy are typically characterised by dermatological disorders such as poor wound healing and tooth loss, but there is not usually cardiac involvement. A case of reversible pulmonary hypertension and right-sided heart failure owing to scurvy in a 7-year-old boy with autism spectrum disorder is reported. He had a very restricted diet and presented with polyarthralgia, gingival hyperplasia with ecchymosis, and fatigue. His condition, including pulmonary hypertension and right-sided heart failure, completely resolved with vitamin C supplementation. Paediatricians should have a high index of suspicion for scurvy in children with nutritional selectivity and be aware that it can manifest with cardiac symptoms. Scurvy may be life-threatening if not treated, but the symptoms can improve rapidly with vitamin C supplementation.
摘要:
镰刀,维生素C缺乏引起的疾病,是罕见的,特别是在高收入国家。镰刀病的症状通常表现为皮肤病,如伤口愈合不良和牙齿脱落,但通常不会有心脏受累。据报道,在一名患有自闭症谱系障碍的7岁男孩中,有一例可逆性肺动脉高压和右心衰。他的饮食非常有限,患有多关节痛,牙龈增生伴瘀斑,和疲劳。他的状况,包括肺动脉高压和右心衰竭,完全解决了补充维生素C。儿科医生应该对具有营养选择性的儿童有很高的怀疑,并意识到它可以表现为心脏症状。如果不治疗的话,镰刀可能会危及生命,但是补充维生素C可以迅速改善症状。
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