PDF(Sci-hub)
Abstract：
It is crucial to replicate or mimic the human digestive system conditions closely in model systems to have the food digestion-related data as accurate as possible. Thus, the data obtained could contribute to studies like those on the relationship between health and nutrition. This review aims to express the human digestion system\'s role in food digestion and compare the capability of the models used in simulations, especially the dynamic in vitro models. Activities of the human digestive system governing food digestion and the food matrix\'s disintegration mechanism in the digestive system were discussed. Dynamic in vitro models and their relevance to the human digestive system were described. Advancements in the last 20 years, as well as limitations of those artificial systems, with prospects, were discussed. Extensive use and improvement on these models will extend our knowledge of the food matrix and digestive system\'s complex interaction. Thus, it will be possible to design next-generation foods with improved health benefits.
摘要：
在模型系统中紧密地复制或模仿人类消化系统条件以使食物消化相关数据尽可能准确至关重要。因此，获得的数据可能有助于健康与营养之间关系的研究。这篇综述旨在表达人类消化系统在食物消化中的作用，并比较模拟中使用的模型的能力。尤其是动态体外模型。讨论了人类消化系统控制食物消化的活动以及消化系统中食物基质的崩解机制。描述了动态体外模型及其与人类消化系统的相关性。过去20年的进步，以及这些人造系统的局限性，有前景,进行了讨论。这些模型的广泛使用和改进将扩展我们对食物基质和消化系统复杂相互作用的认识。因此，将有可能设计出具有改善健康益处的下一代食品。
