PDF(Pubmed)
Abstract：
Lichen nitidus and morphea are common diseases, but an associated localization of both lesions is rare. Here, we describe the first case of lesions distributed along Blaschko\'s lines. A 24-year-old Japanese woman was referred to our clinic for evaluation of band-like plaques of 18-months history on the right lateral side of her abdomen. In addition, multiple milky-white papules were seen within the plaques. Histopathological examination showed there was sclerosis in the lower half of the dermis and well-circumscribed, dense, papillary dermal lymphohistiocytic aggregations showing a so-called \"claw clutching a ball.\" Immunohistochemical analysis revealed that the morphea and lichen nitidus had similar characteristics. We speculated that unique immunologic events led to the development of lichen nitidus and morphea in our patient.
摘要：
扁平苔藓和湿疣是常见病,但是两个病变的相关定位很少见。这里,我们描述了沿Blaschko线分布的第一例病变。一名24岁的日本妇女被转诊到我们的诊所，以评估其腹部右侧18个月病史的带状斑块。此外,斑块内可见多个乳白色丘疹。组织病理学检查显示真皮下半部分有硬化，并且界限清楚，密集,乳头状真皮淋巴组织细胞聚集，显示所谓的“爪抓着球”。“免疫组织化学分析显示，角膜和扁平苔藓具有相似的特征。我们推测，独特的免疫事件导致了我们患者的扁平苔藓和硬皮病的发展。
