PDF(Pubmed)
Abstract：
OBJECTIVE: This paper aims to explore the influences of multi-disciplinary teams (MDT) from the general practitioner\'s (GP\'s) perspective on the clinical efficacy of treating obese patients.
METHODS: Admitted to our hospital from January 2018 to October 2019, 127 obese patients were divided into two groups based on the different models of diagnosis and treatment each underwent. The routine diagnostic and treatment model was administered to the patients in the control group (60 cases), and the MDT model was administered to the patients in the research group (67 cases). The weight loss success rates in both groups were observed. Before and after the treatment, the blood glucose, blood lipid, tumor necrosis factor-α (TNF-α), adiponectin (APN), leptin (LP), and recombinant human fibroblast growth factor 21 (FGF-21) levels were measured. The SAS and SDS scores were evaluated.
RESULTS: After the treatment, the weight loss success rate in the research group was significantly higher than it was in the control group, and the FPG and the 2hPBG levels were significantly lower in the research group. Compared with the control group, the TC, TG, and LDL-C levels were remarkably lower in the study group, and the HDL-C levels were remarkably higher in the research group. The TNF-α, LP, and FGF-21 levels were significantly lower in the research group, and the APN levels were significantly higher. The research group had significantly lower SAS and SDS scores and higher GSES scores.
CONCLUSIONS: MDTs from the GP\'s perspective are conducive to increasing the weight loss success rate and improving the blood glucose, blood lipid and adipokine levels in obese patients.
METHODS: Admitted to our hospital from January 2018 to October 2019, 127 obese patients were divided into two groups based on the different models of diagnosis and treatment each underwent. The routine diagnostic and treatment model was administered to the patients in the control group (60 cases), and the MDT model was administered to the patients in the research group (67 cases). The weight loss success rates in both groups were observed. Before and after the treatment, the blood glucose, blood lipid, tumor necrosis factor-α (TNF-α), adiponectin (APN), leptin (LP), and recombinant human fibroblast growth factor 21 (FGF-21) levels were measured. The SAS and SDS scores were evaluated.
RESULTS: After the treatment, the weight loss success rate in the research group was significantly higher than it was in the control group, and the FPG and the 2hPBG levels were significantly lower in the research group. Compared with the control group, the TC, TG, and LDL-C levels were remarkably lower in the study group, and the HDL-C levels were remarkably higher in the research group. The TNF-α, LP, and FGF-21 levels were significantly lower in the research group, and the APN levels were significantly higher. The research group had significantly lower SAS and SDS scores and higher GSES scores.
CONCLUSIONS: MDTs from the GP\'s perspective are conducive to increasing the weight loss success rate and improving the blood glucose, blood lipid and adipokine levels in obese patients.
摘要：
目的：本文旨在从全科医生（GP）的角度探讨多学科团队（MDT）对肥胖患者临床疗效的影响。
方法：于2018年1月至2019年10月收治的127例肥胖患者，根据诊疗模式的不同分为两组。对照组60例采用常规诊疗模式,研究组患者采用MDT模型(67例)。观察两组的减肥成功率。治疗前后,血糖，血脂，肿瘤坏死因子-α(TNF-α),脂联素（APN），瘦素(LP),检测重组人成纤维细胞生长因子21(FGF-21)水平。评估SAS和SDS评分。
结果：治疗后，研究组减肥成功率明显高于对照组,研究组的FPG和2hPBG水平明显降低。与对照组相比,TC,TG,研究组的LDL-C水平明显降低，研究组的HDL-C水平明显较高。TNF-α,LP,和FGF-21水平在研究组中显著降低，APN水平明显较高。研究组SAS和SDS评分明显较低，GSES评分较高。
结论：从GP的角度来看，MDTs有利于提高减肥成功率和改善血糖，肥胖患者的血脂和脂肪因子水平。
方法：于2018年1月至2019年10月收治的127例肥胖患者，根据诊疗模式的不同分为两组。对照组60例采用常规诊疗模式,研究组患者采用MDT模型(67例)。观察两组的减肥成功率。治疗前后,血糖，血脂，肿瘤坏死因子-α(TNF-α),脂联素（APN），瘦素(LP),检测重组人成纤维细胞生长因子21(FGF-21)水平。评估SAS和SDS评分。
结果：治疗后，研究组减肥成功率明显高于对照组,研究组的FPG和2hPBG水平明显降低。与对照组相比,TC,TG,研究组的LDL-C水平明显降低，研究组的HDL-C水平明显较高。TNF-α,LP,和FGF-21水平在研究组中显著降低，APN水平明显较高。研究组SAS和SDS评分明显较低，GSES评分较高。
结论：从GP的角度来看，MDTs有利于提高减肥成功率和改善血糖，肥胖患者的血脂和脂肪因子水平。
