关键词: deep vascular complex fovea avascular zone fovea plana microvascular 3D visualization technology optical coherence tomography angiography superficial vascular complex

来  源:   DOI:10.3389/fneur.2021.633492   PDF(Pubmed)

Abstract:
This paper aims to study adaptative vascular arrangements in idiopathic fovea plana with volume-rendered optical coherence tomography angiography (OCTA). A retrospective review of two cases of idiopathic fovea plana (mean age: 26.5 years) and two age-matched controls imaged with OCTA was conducted using spectral-domain OCTA (RTVue XR Avanti, Optovue, Inc., Fremont, CA) equipped with the AngioVue software. Both en face OCTA slabs and OCTA b scans were processed through Fiji software (http://fiji.sc; software version 2.0.0-rc-68/1.52e), and then extracted as image sequences for volume rendering reconstructions using the ImageVis3D volume rendering system (3.1.0 release). Eyes with idiopathic fovea plana demonstrated a regular superficial vascular plexus connecting to a single vascular monolayer representing the deeper vascular plexuses. At this location, several vertical short path connections were demonstrated, in contraposition with normal eyes where short path connections were infrequently observed. Advances in three-dimensional OCTA reconstruction increase the understanding of vascular connections and arrangement in retinal plexuses and possible anatomical variations that cannot be detected with conventional two-dimensional b scans.
摘要:
本文旨在通过体积渲染光学相干断层扫描血管造影(OCTA)研究特发性中央凹平面中的适应性血管排列。使用谱域OCTA(RTVueXRAvanti,Optovue,Inc.,弗里蒙特,CA)配备AngioVue软件。正面OCTA平板和OCTAb扫描均通过斐济软件进行处理(http://fiji。sc;软件版本2.0.0-rc-68/1.52e),然后使用ImageVis3D体积渲染系统(3.1.0版本)提取为图像序列进行体积渲染重建。具有特发性中央凹平面的眼睛显示有规则的浅表血管丛连接到单个血管单层,代表较深的血管丛。在这个位置,演示了几个垂直短路径连接,与很少观察到短路径连接的正常眼睛相反。三维OCTA重建的进展增加了对视网膜丛中血管连接和排列以及常规二维b扫描无法检测到的可能解剖变化的理解。
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