Abstract:
We report a 33-year-old man who presented with recurrent right pneumothorax. Computed tomography (CT) showed the presence of a large bulla with a maximum diameter of 8 cm in the right middle lobe; he subsequently underwent bullectomy. Histopathology revealed that pulmonary parenchyma adjacent to the bulla represented nodular proliferation of clear cells characterized by a papillary structure resembling placental chorionic villi. Immunohistochemically, clear cells were positive for CD10, suggesting placental transmogrification of the lung (PTL). We reviewed 36 surgical cases of PTL, and only 2 cases (5.6%), including our case, were operated for spontaneous pneumothorax. Bullous lesions secondary to PTL tend to appear as unilateral large cystic masses in non-upper lobes, which is atypical for primary spontaneous pneumothorax (PSP). Although PTL is considered a very rare cause of secondary pneumothorax, we must carefully differentiate this condition.
摘要:
我们报告了一名33岁的男性,他出现了复发性右侧气胸。计算机断层扫描(CT)显示右中叶存在一个最大直径为8厘米的大疱;他随后接受了大疱切除术。组织病理学显示,与大疱相邻的肺实质代表透明细胞的结节状增殖,其特征是类似胎盘绒毛绒毛的乳头状结构。免疫组织化学,透明细胞CD10呈阳性,提示胎盘肺移位(PTL)。我们回顾了36例PTL手术病例,只有2例(5.6%),包括我们的案子,为自发性气胸手术。PTL继发的大疱性病变倾向于表现为非上叶的单侧大囊性肿块,这是非典型的原发性自发性气胸(PSP)。尽管PTL被认为是继发性气胸的非常罕见的原因,我们必须仔细区分这种情况。