关键词: Asthma Asthma disparities Endocrine-disrupting compounds Personal care products

Mesh : African Americans Asthma / epidemiology Cosmetics / adverse effects Endocrine Disruptors Humans Parabens

来  源:   DOI:10.1016/j.jaip.2021.04.063   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
An evolving body of literature links chemicals commonly found in personal care products (PCPs) to an increased risk of both developing asthma and worsening existing asthma. Phthalates, parabens, environmental phenols, such as triclosan and bisphenol A, and other endocrine-disrupting compounds have been implicated in asthma and related allergic conditions in epidemiological studies. Because Black individuals have increased exposure to these chemicals through hair care products and feminine hygiene products, disproportionate exposure to these chemicals through PCPs could contribute, in part, to the disproportionate asthma prevalence and morbidity among the U.S. Black population. Increased exposure to these chemicals among Black individuals is explained, in part, by more frequent use of hair care products that can contain higher concentrations of these chemicals and greater use of feminine hygiene products, which are also sources of exposure to these chemicals. Epidemiological evidence using urinary biomarkers of exposure demonstrates associations between PCPs and exposure to these chemicals and that the U.S. Black population has greater exposure to these chemicals than the non-Black population. Should chemical exposures through PCPs contribute to the excess burden of asthma among the U.S. Black population, reducing these exposures would reduce this disparity.
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