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Abstract：
The main objective of this research is to determine the psychosocial differences between patients with knee pain or early osteoarthritis (EOA) and healthy subjects at risk of developing osteoarthritis. The secondary objective is to determine how psychosocial factors might influence pain and social participation in patients with EOA. A cross-sectional study was performed. Participants were divided according to the presence of pain or EOA. Pain intensity both at rest and walking, psychological variables such as anxiety and depression, and social participation were evaluated. A total of 105 participants were included (64 with knee pain and 41 without pain), with a mean age of 51.42 ± 5.92 (35 men and 70 women). Patients with knee pain had higher levels of anxiety (MD = -2.35; p < 0.01; d = 0.66) and depression (MD = -2.45; p < 0.01; d = 0.87), regardless of the presence of EOA. In addition, patients with higher depression levels had lower levels of social participation. The results revealed a relationship between the psychological variables, anxiety and depression, with knee pain and the onset of symptomatic OA, as well as an influence of depression levels on social participation. Improving these psychological characteristics may be useful in delaying the onset of symptomatic OA and enhancing social participation.
摘要：
这项研究的主要目的是确定膝关节疼痛或早期骨关节炎（EOA）患者与有患骨关节炎风险的健康受试者之间的心理社会差异。次要目标是确定心理社会因素如何影响EOA患者的疼痛和社会参与。进行了横断面研究。参与者根据疼痛或EOA的存在进行分组。休息和行走时的疼痛强度，心理变量，如焦虑和抑郁，并对社会参与进行了评估。共纳入105名参与者（64名有膝盖疼痛，41名无痛），平均年龄51.42±5.92(35男70女)。膝关节疼痛患者的焦虑水平（MD=-2.35;p<0.01;d=0.66）和抑郁水平（MD=-2.45;p<0.01;d=0.87）较高，不管EOA的存在。此外,抑郁水平较高的患者的社会参与水平较低.结果揭示了心理变量之间的关系，焦虑和抑郁,膝关节疼痛和有症状的OA发作，以及抑郁水平对社会参与的影响。改善这些心理特征可能有助于延迟有症状的OA的发作和增强社会参与。
