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Abstract：
UNASSIGNED: Initial orthostatic hypotension is a clinically relevant syndrome in older adults which has been associated with symptoms of orthostatic intolerance. The aim of this systematic review was to determine the prevalence of orthostatic intolerance symptoms in older adults with initial orthostatic hypotension.
UNASSIGNED: MEDLINE (from 1946), EMBASE (from 1974) and Cochrane were searched to December 6th, 2019 using the terms \"initial orthostatic hypotension\", \"postural hypotension\" and \"older adults\". Study selection involved the following criteria: published in English; mean or median age ≥ 65 years and diagnosis of initial orthostatic hypotension encompassed a decrease in systolic blood pressure by ≥ 40 mmHg and/or diastolic blood pressure by ≥ 20 mmHg within a maximum of 1 min following a postural change.
UNASSIGNED: Of 8311 articles, 12 articles reporting initial orthostatic hypotension prevalence in 3446 participants with a mean age of 75 (6 SD) years (56.5% female) were included. Five initial orthostatic hypotension definition variations were utilised and symptoms were reported in six articles (968 participants, mean age 73.4 (6.1 SD) years, 56% female). The prevalence of symptoms in older adults with initial orthostatic hypotension ranged from 24 to 100% and was dependent on variations in timing or the inclusion of symptoms in the initial orthostatic hypotension definition.
UNASSIGNED: Where orthostatic intolerance symptoms were reported, a large proportion of older adults with a diagnosis of initial orthostatic hypotension were symptomatic. However, the literature on initial orthostatic hypotension and orthostatic intolerance symptoms is scarce and a variety of definitions of initial orthostatic hypotension are utilised.
UNASSIGNED: MEDLINE (from 1946), EMBASE (from 1974) and Cochrane were searched to December 6th, 2019 using the terms \"initial orthostatic hypotension\", \"postural hypotension\" and \"older adults\". Study selection involved the following criteria: published in English; mean or median age ≥ 65 years and diagnosis of initial orthostatic hypotension encompassed a decrease in systolic blood pressure by ≥ 40 mmHg and/or diastolic blood pressure by ≥ 20 mmHg within a maximum of 1 min following a postural change.
UNASSIGNED: Of 8311 articles, 12 articles reporting initial orthostatic hypotension prevalence in 3446 participants with a mean age of 75 (6 SD) years (56.5% female) were included. Five initial orthostatic hypotension definition variations were utilised and symptoms were reported in six articles (968 participants, mean age 73.4 (6.1 SD) years, 56% female). The prevalence of symptoms in older adults with initial orthostatic hypotension ranged from 24 to 100% and was dependent on variations in timing or the inclusion of symptoms in the initial orthostatic hypotension definition.
UNASSIGNED: Where orthostatic intolerance symptoms were reported, a large proportion of older adults with a diagnosis of initial orthostatic hypotension were symptomatic. However, the literature on initial orthostatic hypotension and orthostatic intolerance symptoms is scarce and a variety of definitions of initial orthostatic hypotension are utilised.
摘要：
■初始直立性低血压是老年人的临床相关综合征，与直立性不耐受症状有关。本系统评价的目的是确定初始体位性低血压的老年人体位不耐受症状的患病率。
■MEDLINE（自1946年起），EMBASE（从1974年开始）和Cochrane被搜索到12月6日，2019年使用术语“初始直立性低血压”，“体位性低血压”和“老年人”。研究选择涉及以下标准：以英语发表；平均年龄或中位年龄≥65岁，初始直立性低血压的诊断包括在姿势改变后的最多1分钟内收缩压降低≥40mmHg和/或舒张压降低≥20mmHg。
■在8311篇文章中，纳入了12篇报告3446名平均年龄为75（6SD）岁的参与者（56.5％为女性）的初始直立性低血压患病率的文章。使用了五个初始的直立性低血压定义变化，并在六篇文章中报告了症状（968名参与者，平均年龄73.4(6.1标准差)岁，56%女性）。初始体位性低血压的老年人症状的患病率为24％至100％，取决于时间的变化或初始体位性低血压定义中的症状。
■在报告体位不耐受症状的地方，大部分被诊断为初始直立性低血压的老年人有症状.然而,关于初始直立性低血压和直立性不耐受症状的文献很少，并且使用了各种初始直立性低血压的定义。
■MEDLINE（自1946年起），EMBASE（从1974年开始）和Cochrane被搜索到12月6日，2019年使用术语“初始直立性低血压”，“体位性低血压”和“老年人”。研究选择涉及以下标准：以英语发表；平均年龄或中位年龄≥65岁，初始直立性低血压的诊断包括在姿势改变后的最多1分钟内收缩压降低≥40mmHg和/或舒张压降低≥20mmHg。
■在8311篇文章中，纳入了12篇报告3446名平均年龄为75（6SD）岁的参与者（56.5％为女性）的初始直立性低血压患病率的文章。使用了五个初始的直立性低血压定义变化，并在六篇文章中报告了症状（968名参与者，平均年龄73.4(6.1标准差)岁，56%女性）。初始体位性低血压的老年人症状的患病率为24％至100％，取决于时间的变化或初始体位性低血压定义中的症状。
■在报告体位不耐受症状的地方，大部分被诊断为初始直立性低血压的老年人有症状.然而,关于初始直立性低血压和直立性不耐受症状的文献很少，并且使用了各种初始直立性低血压的定义。
