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Abstract：
Recurrent implantation failure (RIF) is defined as the absence of a positive pregnancy test after three consecutive transfers of good quality embryos. There remains significant variation in clinical practice in the management of RIF. This British Fertility Society (BFS) Policy and Practice guideline analyses the evidence for investigations and therapies that are employed in RIF and provides recommendations for clinical practice and for further research. Evidence for investigations of sperm and egg quality, uterine and adnexal factors, immunological factors and thrombophilia, endocrine conditions and genetic factors and for associated therapies have been evaluated. This guideline has been devised to assist reproductive medicine specialists and patients in making shared decisions concerning management of RIF. Finally, suggestions for research towards improving understanding and management of RIF have also been provided.
摘要：
复发性植入失败(RIF)被定义为在连续三次移植高质量胚胎后没有阳性妊娠试验。RIF的管理在临床实践中仍然存在显著差异。英国生育协会（BFS）政策和实践指南分析了RIF中采用的调查和治疗的证据，并为临床实践和进一步研究提供了建议。精子和卵子质量调查的证据，子宫和附件因素，免疫因素和血栓形成倾向，已经评估了内分泌条件和遗传因素以及相关疗法。本指南旨在帮助生殖医学专家和患者就RIF的管理做出共同决定。最后,还提供了研究建议，以提高对RIF的理解和管理。
