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Abstract：
OBJECTIVE: This systematic review was aimed to find out possible predictive variables measured on panoramic radiographs to predict spontaneous eruption of palatally displaced canine (PDC) after interceptive extraction in late mixed dentition.
METHODS: Electronic database searches were performed in MEDLINE, Cochrane\'s CENTRAL, Scopus, and in other sources up to June 2020. Randomized and nonrandomized controlled trials, and pre-post prospective studies without control groups were considered for review. Study selection, data extraction, risk of bias assessment (by RoB 2.0, ROBINS-I, and NHLBI score), and the certainty of evidence evaluation (GRADE approach) were performed during reviewing process. Only qualitative analyses of included literature were done due to presence of between study heterogeneity.
RESULTS: Out of 970 retrieved records, 3 controlled trials and 3 prospective before and after studies without control fulfilled the eligibility criteria and were included in the review. Studies were assessed at low risk to high risk of bias. Overall certainty was moderate to very low. Results shows that PDCs in distal sectors, lower alpha angle, younger subjects, PDCs with less advanced developed root were significantly benefited from interceptive extraction. However, Vertical distance had insignificant roll on eruption prediction.
CONCLUSIONS: Interceptive extraction at younger age, mesial canine crown position (sectors), and mesial inclination of PDC (alpha angulation) are the most important variables predicting the spontaneous eruption of palatally displaced canine. Findings of this review can be utilized to make evidence-based decisions for managing PDCs with diverse sectors and mesial inclinations. However, well designed clinical trials are recommended to strengthen the evidence.
METHODS: Electronic database searches were performed in MEDLINE, Cochrane\'s CENTRAL, Scopus, and in other sources up to June 2020. Randomized and nonrandomized controlled trials, and pre-post prospective studies without control groups were considered for review. Study selection, data extraction, risk of bias assessment (by RoB 2.0, ROBINS-I, and NHLBI score), and the certainty of evidence evaluation (GRADE approach) were performed during reviewing process. Only qualitative analyses of included literature were done due to presence of between study heterogeneity.
RESULTS: Out of 970 retrieved records, 3 controlled trials and 3 prospective before and after studies without control fulfilled the eligibility criteria and were included in the review. Studies were assessed at low risk to high risk of bias. Overall certainty was moderate to very low. Results shows that PDCs in distal sectors, lower alpha angle, younger subjects, PDCs with less advanced developed root were significantly benefited from interceptive extraction. However, Vertical distance had insignificant roll on eruption prediction.
CONCLUSIONS: Interceptive extraction at younger age, mesial canine crown position (sectors), and mesial inclination of PDC (alpha angulation) are the most important variables predicting the spontaneous eruption of palatally displaced canine. Findings of this review can be utilized to make evidence-based decisions for managing PDCs with diverse sectors and mesial inclinations. However, well designed clinical trials are recommended to strengthen the evidence.
摘要：
■这项系统评价旨在找出在全景X射线照片上测量的可能的预测变量，以预测在晚期混合牙列中拦截式拔除后，pat位移位的犬（PDC）的自发爆发。
■在MEDLINE中进行电子数据库搜索，科克伦中心,Scopus,以及截至2020年6月的其他来源。随机和非随机对照试验，并且考虑了没有对照组的前瞻性研究进行回顾。研究选择，数据提取,偏见风险评估(根据RoB2.0，ROBINS-I，和NHLBI得分），在审查过程中进行了证据确定性评估(等级方法)。由于研究之间存在异质性，仅对纳入文献进行定性分析。
■在970条检索记录中，3个对照试验和3个无对照的前瞻性前后研究符合资格标准，并纳入审查。研究被评估为低风险到高风险的偏倚。总体确定性中等到非常低。结果表明，远端扇区的PDC，较低的α角,年轻的科目，根较不发达的PDC从拦截提取中显着受益。然而,垂直距离对喷发预测的影响不大。
■在较年轻的年龄进行拦截提取，近中犬冠位置（扇区），PDC的近倾角（α角）是预测pal位犬科动物自发爆发的最重要变量。这项审查的结果可用于做出基于证据的决策，以管理具有不同部门和中等倾向的PDC。然而,精心设计的临床试验建议加强证据。
■在MEDLINE中进行电子数据库搜索，科克伦中心,Scopus,以及截至2020年6月的其他来源。随机和非随机对照试验，并且考虑了没有对照组的前瞻性研究进行回顾。研究选择，数据提取,偏见风险评估(根据RoB2.0，ROBINS-I，和NHLBI得分），在审查过程中进行了证据确定性评估(等级方法)。由于研究之间存在异质性，仅对纳入文献进行定性分析。
■在970条检索记录中，3个对照试验和3个无对照的前瞻性前后研究符合资格标准，并纳入审查。研究被评估为低风险到高风险的偏倚。总体确定性中等到非常低。结果表明，远端扇区的PDC，较低的α角,年轻的科目，根较不发达的PDC从拦截提取中显着受益。然而,垂直距离对喷发预测的影响不大。
■在较年轻的年龄进行拦截提取，近中犬冠位置（扇区），PDC的近倾角（α角）是预测pal位犬科动物自发爆发的最重要变量。这项审查的结果可用于做出基于证据的决策，以管理具有不同部门和中等倾向的PDC。然而,精心设计的临床试验建议加强证据。
