Abstract:
In this study, we investigated spatial diversities of sexually transmitted infections (STIs) and quantified their impacts on the STIs using population attributable risk (PAR%). The study population was 7,557 women who participated in several HIV prevention trials from KwaZulu-Natal, South Africa. Our results provide compelling evidence for substantial geographical diversities on STI incidence rates in the region. Their population-level impacts on the STIs exceeded the combined impacts of the individual risk factors considered in this study (PAR%: 41% (<25 years), 52% (25-34 years) and 34% (35+ years). When all these factors are considered together, PAR% was the highest among younger women (PAR%: 67%, 82% and 50% for <25, 25-34 and 35+ years old respectively). Results from our study will bring greater insight into the previous research by increasing our understanding of the impacts of the sub-geographical level variations of STI prevalence and incidence rates in the region.
摘要:
在这项研究中,我们调查了性传播感染(STIs)的空间多样性,并使用人群归因风险(PAR%)量化了其对STIs的影响.研究人群是7,557名妇女,他们参加了夸祖鲁-纳塔尔省的几项艾滋病毒预防试验。南非。我们的结果为该地区性传播感染发病率的地理差异提供了令人信服的证据。他们对性传播感染的人口水平影响超过了本研究中考虑的个体风险因素的综合影响(PAR%:41%(<25年),52%(25-34岁)和34%(35岁以上)。当所有这些因素一起考虑时,PAR%在年轻女性中最高(PAR%:67%,<25岁、25-34岁和35岁以上分别为82%和50%)。通过增加我们对该地区性传播感染患病率和发病率的亚地理水平变化的影响的理解,我们的研究结果将使我们对以前的研究有更多的了解。