Abstract：
Peripheral T-cell lymphoma (PTCL) is an aggressive tumor, rarely seen in pediatrics or adolescent and young adults (AYAs) so there is no upfront or relapsed standard of care. The authors describe a 16-year-old with PTCL, treated with chemotherapy and autologous stem cell transplant. Upon relapse, he received ifosfamide, carboplatin, etoposide, and radiation with durable remission of 4 years. Data in pediatric/AYA PCTL continue to lack an understanding of the biology and microenvironment, the differences to adult patients, and a lack of adequate therapy. Targeted therapy may improve outcomes for children and AYAs with refractory or relapsed PTCL.
摘要：
外周T细胞淋巴瘤（PTCL）是一种侵袭性肿瘤，在儿科或青少年和年轻人（AYAs）中很少见，因此没有预先或复发的护理标准。作者描述了一名16岁的PTCL患者，化疗和自体干细胞移植治疗。一旦复发，他接受了异环磷酰胺,卡铂,依托泊苷,和辐射可持续缓解4年。儿科/AYAPCTL的数据仍然缺乏对生物学和微环境的了解，与成年患者的差异，缺乏足够的治疗。靶向治疗可以改善儿童和患有难治性或复发性PTCL的AYAs的预后。
