PDF(Pubmed)
Abstract：
Primary mucinous tumors of the testis and paratestis are very rare, with only 29 reported cases detected in a PubMed search. The histopathological characteristics of primary testicular mucinous tumors are similar to their ovarian counterparts, and the diagnosis and naming criteria refer to the criteria for female ovarian mucinous tumors. However, the clinical and imaging features of primary testicular mucinous tumors are poorly understood, and they are thus frequently undiagnosed or misdiagnosed. We present the case of a patient with a primary testicular mucinous tumor. A 52-year-old man presented with a 1-year history of painless enlargement of the left scrotum. Ultrasound examination revealed a cystic mass in the left testis, with viscous fluid areas and calcified spots, irregular solid bulges on the cyst wall, and a small blood supply. Serum alpha-fetoprotein, β-human chorionic gonadotropin, lactate dehydrogenase, renal function, inflammatory markers, and routine urine and blood examinations were all normal. The patient underwent radical resection of the left testis. Postoperative pathology showed a multilocular cystic mass, with the inner wall of the sac lined with mucous columnar epithelial cells, some with mild nuclear atypia, and no interstitial infiltration. The pathological diagnosis was testicular mucinous tumor. Postoperative abdominal and pelvic computed tomography, colonoscopy, and gastroscopy showed no suspicious lesions. The final diagnosis was primary testicular borderline mucinous tumor. The patient underwent postoperative follow-up examinations once a year for 4 years. Serum tumor markers, scrotal ultrasound, abdominal and pelvic computed tomography scans, and colonoscopy and gastroscopy revealed no evidence of metastases or other primary adenocarcinoma. This case highlights the clinical and imaging characteristics of primary testicular mucinous tumors, which might aid their differential diagnosis.
摘要：
睾丸和睾丸的原发性粘液性肿瘤非常罕见，在PubMed搜索中只检测到29例报告病例。原发性睾丸黏液性肿瘤的组织病理学特征与卵巢相似，诊断和命名标准参考女性卵巢粘液性肿瘤的标准。然而,原发性睾丸粘液性肿瘤的临床和影像学特征知之甚少，因此，他们经常得不到诊断或误诊。我们介绍了一名原发性睾丸粘液性肿瘤患者的病例。一名52岁的男子，有1年的左阴囊无痛肿大史。超声检查发现左侧睾丸有囊性肿块,有粘稠的液体区域和钙化点，囊肿壁上有不规则的实体凸起，和少量的血液供应。血清甲胎蛋白，β-人绒毛膜促性腺激素,乳酸脱氢酶,肾功能,炎症标志物，尿常规、血常规检查均正常。患者接受左睾丸根治性切除术。术后病理显示为多房性囊性肿块，囊的内壁衬有粘液柱状上皮细胞，一些患有轻度核非典型性，没有间质浸润.病理诊断为睾丸黏液性肿瘤。术后腹部和盆腔计算机断层扫描，结肠镜检查,胃镜检查未见可疑病变。最终诊断为原发性睾丸交界性粘液性肿瘤。患者每年接受一次术后随访检查，为期4年。血清肿瘤标志物,阴囊超声,腹部和盆腔计算机断层扫描，结肠镜和胃镜检查未发现转移或其他原发性腺癌的证据。此病例突出了原发性睾丸黏液性肿瘤的临床和影像学特点,这可能有助于他们的鉴别诊断。
