关键词: Nail bed Nail matrix Nail psoriasis Nail psoriasis treatment

Mesh : Arthritis, Psoriatic Humans Nail Diseases / drug therapy Nails Psoriasis / drug therapy Quality of Life

来  源:   DOI:10.1016/j.det.2020.12.014   PDF(Sci-hub)

Abstract:
Nail psoriasis is a chronic nail disorder that requires personalized treatment. General prophylactic measures are suggested for all patients. Topical treatment is considered when treating a few-nail disease, with involvement of 3 or fewer nails, without joint involvement and without (or with mild) skin psoriasis. The ideal formulation should be ointment, solution, or foam. When moderate to severe skin psoriasis or psoriatic arthritis coexists, systemic treatment is suggested. This also should be considered when more than 3 nails are affected or significant impairment of quality of life is present. Conventional systemic agents, biologics, and small molecules are highly efficacious.
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