The guideline committee discussed and drew up a series of clinical questions (CQs). Recommendation statements for the CQs were limited to items with multiple therapeutic options. Items with established conclusions that had 100% agreement with previous guidelines (background questions) and items with no (or old) evidence that are topics for future research (future research questions: FRQs) were given descriptions only. To address the CQs and FRQs, PubMed, ICHUSHI, and other sources were searched for relevant articles published in English from 1983 to October 2018 and articles published in Japanese from 1983 to November 2018. The Japan Medical Library Association was also commissioned to search for relevant materials. Manual searches were performed for questions with insufficient online references.
The professional committee created 18 CQs and statements concerning the current concept and diagnosis/treatment of various colorectal polyps, including their epidemiology, screening, pathophysiology, definition and classification, diagnosis, management, practical treatment, complications, and surveillance after treatment, and other colorectal lesions (submucosal tumors, nonneoplastic polyps, polyposis, hereditary tumors, ulcerative colitis-associated tumors/carcinomas).
After evaluation by the moderators, evidence-based clinical practice guidelines for management of colorectal polyps were proposed for 2020. This report addresses the therapeutic related CQs introduced when formulating these guidelines.
指南委员会讨论并起草了一系列临床问题(CQs)。CQ的推荐声明仅限于具有多种治疗选择的项目。与以前的指南(背景问题)具有100%一致性的既定结论的项目以及没有(或旧的)证据的项目(未来研究问题:FRQ)仅给出描述。要解决CQ和FRQ,PubMed,ICHUSHI,搜索了1983年至2018年10月以英文发表的相关文章和1983年至2018年11月以日文发表的文章。还委托日本医学图书馆协会搜索相关资料。对在线参考不足的问题进行了手动搜索。
专业委员会创建了18个CQs和关于各种结直肠息肉的当前概念和诊断/治疗的声明,包括他们的流行病学,筛选,病理生理学,定义和分类,诊断,管理,实际治疗,并发症,治疗后的监测,和其他结肠直肠病变(粘膜下肿瘤,非肿瘤性息肉,息肉病,遗传性肿瘤,溃疡性结肠炎相关肿瘤/癌)。
经过主持人的评估,我们提出了2020年基于循证的结直肠息肉治疗临床实践指南.本报告介绍了在制定这些指南时引入的与治疗相关的CQ。