Nutrition in Chronic Liver Disease: Consensus Statement of the Indian National Association for Study of the Liver.

慢性肝病的营养 ： 印度全国肝脏研究协会的共识声明。

• 发表时间: Jan-Feb 2021
• 来源期刊: J Clin Exp Hepatol
• DOI: 10.1016/j.jceh.2020.09.003
• PMID: 33679050
• 文章类型: Journal Article
• 作者列表: Puri P,Dhiman RK,Taneja S,Tandon P,Merli M,Anand AC,Arora A,Acharya SK,Benjamin J,Chawla YK,Dadhich S,Duseja A,Eapan CE,Goel A,Kalra N,Kapoor D,Kumar A,Madan K,Nagral A,Pandey G,Rao PN,Saigal S,Saraf N,Saraswat VA,Saraya A,Sarin SK,Sharma P,Shalimar ,Shukla A,Sidhu SS,Singh N,Singh SP,Srivastava A,Wadhawan M

关键词: ACLF, acute on chronic liver failure; ASM, appendicular skeletal muscle mass; BCAA, branched chain amino acids; BIA, bioimpedance analysis; BMD, bone mineral densitometry; BMI, body mass index; CLD, chronic liver disease; CS, corn-starch; CT, computed tomography; CTP, Child–Turcotte–Pugh; DEXA, dual-energy X-ray absorptiometry; EASL, European Association for the Study of the Liver; ESPEN, European society for Clinical Nutrition and Metabolism; GSD, glycogen storage disease; HGS, hand-grip strength; IBW, ideal body weight; IEM, inborn error of metabolism; INASL, Indian National Association for Study of the Liver; L3, third lumbar; LFI, Liver Frailty Index; MCT, medium-chain triglyceride; MELD, model for end-stage liver disease; MLD, metabolic liver disease; MRI, magnetic resonance imaging; RDA, recommended daily allowance; REE, NASH; RFH-NPT, Royal Free Hospital-Nutritional Prioritizing Tool; SMI, skeletal muscle index; Sarcopenia; TEE, total energy expenditure; chronic liver disease; cirrhosis; malnutrition; non-alcoholic liver disease, resting energy expenditure; nutrition

Abstract

Malnutrition and sarcopenia are common in patients with chronic liver disease and are associated with increased risk of decompensation, infections, wait-list mortality and poorer outcomes after liver transplantation. Assessment of nutritional status and management of malnutrition are therefore essential to improve outcomes in patients with chronic liver disease. This consensus statement of the Indian National Association for Study of the Liver provides a comprehensive review of nutrition in chronic liver disease and gives recommendations for nutritional screening and treatment in specific clinical scenarios of malnutrition in cirrhosis in adults as well as children with chronic liver disease and metabolic disorders.

摘要

营养不良和肌肉减少症在慢性肝病患者中很常见，并且与失代偿风险增加有关。感染,等待名单死亡率和肝移植后较差的结局.因此，营养状况评估和营养不良管理对于改善慢性肝病患者的预后至关重要。印度全国肝脏研究协会的共识声明对慢性肝病的营养进行了全面审查，并在成人以及患有慢性肝病和代谢紊乱的儿童的肝硬化营养不良的特定临床情况下提供了营养筛查和治疗建议。