Abstract：
Talaromyces marneffei infection is an AIDS-defining illness in South and Southeast Asia. Travel-related talaromycosis is being increasingly recognized in non-endemic areas too. It is a potentially fatal infection with rapid deterioration, if left untreated. Usage of Tzanck cytology smear for rapid diagnosis of T. marneffei is rarely described. In this case study, we report a man who presented with altered behaviour, headache, fever and cutaneous lesions. Tzanck smear test, skin biopsy and blood culture showed presence of T. marneffei. The cytomorphology findings of T. marneffei in Tzanck cytology smear were described. In conclusion, Tzanck smear is a simple and inexpensive test in establishing a rapid clinical diagnosis of talaromycosis before the culture is reported.
摘要：
马尔尼菲塔拉菌感染是南亚和东南亚的一种定义为艾滋病的疾病。在非流行地区，与旅行相关的talarycosis也得到了越来越多的认可。这是一种快速恶化的潜在致命感染，如果不及时治疗。很少描述Tzanck细胞学涂片用于快速诊断马尼菲。在这个案例研究中,我们报告一个人的行为发生了改变，头痛,发烧和皮肤损伤。Tzanck涂片试验,皮肤活检和血培养显示存在马尔尼菲。描述了T.marneffi在Tzanck细胞学涂片中的细胞形态学发现。总之,Tzanck涂片是一种简单而廉价的测试，可在报告培养之前建立对talaryomcosis的快速临床诊断。
