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Abstract：
BACKGROUND: There are no guidelines to screen haemato-oncologic children when a tuberculosis (TB) outbreak is suspected.
METHODS: After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8-12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up.
RESULTS: After 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients.
CONCLUSIONS: The TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations.
METHODS: After exposition to an adult with active TB, children exposed from a haemato-oncology unit were screened according to immunosuppression status and time of exposure. Until an evaluation after 8-12 weeks from last exposure, isoniazid was indicated to those with negative initial work-up.
RESULTS: After 210 interventions, we detected a case of pulmonary TB, and another with latent TB infection. Pulmonary findings and treatment approach were challenging in some patients.
CONCLUSIONS: The TB screening of oncologic children required a multidisciplinary approach, and clinicians managed challenging situations.
摘要：
背景：当怀疑结核病（TB）爆发时，没有筛查血液肿瘤患儿的指南。
方法：在对患有活动性结核病的成年人进行阐述后，根据免疫抑制状态和暴露时间对血液肿瘤科暴露儿童进行筛查.直到最后一次暴露8-12周后进行评估，异烟肼适用于初始检查阴性的患者。
结果：经过210次干预，我们发现了一例肺结核,另一个患有潜伏性结核感染。在某些患者中，肺部检查结果和治疗方法具有挑战性。
结论：肿瘤患儿的结核病筛查需要多学科方法，和临床医生管理具有挑战性的情况。
方法：在对患有活动性结核病的成年人进行阐述后，根据免疫抑制状态和暴露时间对血液肿瘤科暴露儿童进行筛查.直到最后一次暴露8-12周后进行评估，异烟肼适用于初始检查阴性的患者。
结果：经过210次干预，我们发现了一例肺结核,另一个患有潜伏性结核感染。在某些患者中，肺部检查结果和治疗方法具有挑战性。
结论：肿瘤患儿的结核病筛查需要多学科方法，和临床医生管理具有挑战性的情况。
