关键词: (155)Tb (165)Er Auger electrons ISOL facility Production of medical isotopes Targeted radionuclide therapy

Mesh : Radioisotopes / chemistry Radiochemistry / methods instrumentation Terbium / chemistry Humans

来  源:   DOI:10.1016/j.nucmedbio.2021.01.003   PDF(Sci-hub)

Abstract:
Production of medical radionuclides with ISOL facilities is a unique production method that may provide access to preclinical quantities of some rare and potent radionuclides for nuclear medicine. Particularly attention over the past years was focused on several promising candidates for Targeted Radionuclides Therapy (TRT). With this review, we provide some perspectives of using the TRIUMF ISOL facility (ISAC) to produce medical radionuclides for TRT application and highlight our current effort to collect of 165Er and 155Tb for Auger Therapy and SPECT imaging, respectively.
摘要:
使用ISOL设施生产医用放射性核素是一种独特的生产方法,可以为核医学提供临床前数量的一些稀有和有效的放射性核素。在过去的几年中,特别关注的是靶向放射性核素治疗(TRT)的几个有希望的候选人。通过这次审查,我们提供了使用TRIUMFISOL设施(ISAC)为TRT应用生产医用放射性核素的一些观点,并强调了我们目前为俄歇疗法和SPECT成像收集165Er和155Tb的努力,分别。
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