关键词: Mauritania Nouakchott actinomycetoma eumycetoma mycetoma

Mesh : Adult Female Health Facilities Hospitals Humans Male Mauritania / epidemiology Mycetoma / diagnosis drug therapy epidemiology Retrospective Studies

来  源:   DOI:10.1093/trstmh/traa197   PDF(Sci-hub)

Abstract:
Mycetoma is a chronic, progressive and destructive inflammatory disease that affects the skin, subcutaneous and other tissues. The objective of this study was to identify all cases of mycetoma diagnosed in three health facilities in Nouakchott, Mauritania during 2016-2018.
This retrospective hospital-based study was conducted at the Dermatology, Orthopedics, Mycology and Pathology departments of the National Hospital Center of Nouakchott, the Military Hospital of Nouakchott and the National Institute for Research in Public Health of Nouakchott.
Eighty-seven patients were included in this study. They comprised 65 male patients (74.71%) and 22 females (25.28%) with a gender ratio of 4:1. The mean age was 41.87 y and ages ranged from 14 to 70 y. The most common age group was 40-45 y (11%). The foot was the most frequently affected site seen in 60 patients (69%), followed by ankle and hand with 6 patients each (7%). In the study, 56 patients (64%) had regional lymphadenopathy. Forty-nine patients (56%) had bone involvement. Thirty-two patients (37%) had medical treatment. Twenty-seven patients (87%) received fluconazole and four patients (13%) had co-trimoxazole treatment.
The mycetoma patients seen in these three centres were mainly male farmers from rural areas. The lesions were seen mainly in the lower limbs and the majority had bone involvement radiologically.
摘要:
Mycetoma是一种慢性,影响皮肤的进行性和破坏性炎症性疾病,皮下和其他组织。这项研究的目的是确定在努瓦克肖特的三个医疗机构中诊断出的所有肌瘤病例,毛里塔尼亚2016-2018年。
这项以医院为基础的回顾性研究是在皮肤科进行的,骨科,努瓦克肖特国家医院中心真菌学和病理科,努瓦克肖特军事医院和努瓦克肖特国家公共卫生研究所。
本研究包括87名患者。他们包括65名男性患者(74.71%)和22名女性(25.28%),性别比例为4:1。平均年龄为41.87岁,年龄为14至70岁。最常见的年龄组为40-45岁(11%)。足部是60例患者(69%)中最常受影响的部位,其次是踝关节和手部,各6例(7%)。在研究中,56例患者(64%)有区域淋巴结病。49例患者(56%)有骨受累。32名患者(37%)接受了药物治疗。27名患者(87%)接受了氟康唑治疗,4名患者(13%)接受了复方新诺明治疗。
在这三个中心看到的肌瘤患者主要是来自农村地区的男性农民。病变主要见于下肢,大多数在放射学上有骨受累。
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