关键词: Diagnosis Guideline Ovarian cancer Treatment

Mesh : Antineoplastic Agents, Immunological / therapeutic use Bevacizumab / therapeutic use Carcinoma, Ovarian Epithelial / diagnosis pathology therapy Chemotherapy, Adjuvant / methods Clinical Trials, Phase III as Topic Cytoreduction Surgical Procedures / methods Female Humans Maintenance Chemotherapy / methods Medical Oncology Neoplasm Recurrence, Local / drug therapy surgery Neoplasm Staging / methods Ovarian Neoplasms / diagnosis pathology therapy Poly(ADP-ribose) Polymerase Inhibitors / therapeutic use Randomized Controlled Trials as Topic Societies, Medical Spain

来  源:   DOI:10.1007/s12094-020-02545-x   PDF(Pubmed)

Abstract:
Despite remarkable advances in the knowledge of molecular biology and treatment, ovarian cancer remains the leading cause of death from gynecologic cancer. In the last decade, there have been important advances both in systemic and surgical treatment. However, there is no doubt that the incorporation of PARP inhibitors as maintenance after the response to platinum-based chemotherapy, first in recurrent disease and recently also in first line, will change the natural history of the disease.The objective of this guide is to summarize the current evidence for the diagnosis, treatment, and follow-up of ovarian cancer, and to provide evidence-based recommendations for clinical practice.
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